NCT02825303

Brief Summary

Prolonged sitting is a risk factor for cardiovascular and musculoskeletal diseases, diabetes, several types of cancer and all-cause mortality. In combination with static and awkward postures, the prevalence of musculoskeletal diseases can increase further. Although the implementation of sit-to-stand or active workstations can help to reduce sitting time, improve physical activity at work and promote health benefits, it might also lead to changes in cognitive functions such as productivity The purpose of this study is to evaluate the mid-term effect of a novel two desk sit-to-stand workplace on sitting time as well as physiological and cognitive parameters for healthy people of working age in comparison to their traditional workplace.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
18

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2014

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2014

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2015

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

July 4, 2016

Completed
3 days until next milestone

First Posted

Study publicly available on registry

July 7, 2016

Completed
Last Updated

July 15, 2016

Status Verified

July 1, 2016

Enrollment Period

1.2 years

First QC Date

July 4, 2016

Last Update Submit

July 14, 2016

Conditions

Keywords

postural changesHeight adjustable deskProlonged sittingCognitive performance

Outcome Measures

Primary Outcomes (1)

  • Daily sitting time

    Changes in sitting time after 23 weeks in the experimental group compared with its own control period and the control group. Measuring methods: International Physical Activity Questionaire (IPAQ); self developed tracking software at the participants' workplace

    baseline and 23 weeks

Secondary Outcomes (1)

  • Cognitive performance (composite outcome)

    baseline and 23 weeks

Other Outcomes (1)

  • Stress response

    baseline and 23 weeks

Study Arms (3)

Novel workplace - first half

EXPERIMENTAL

Intervention: A novel two-desk sit-to-stand workstation for 23 weeks; provided within the first half of the study. Traditional workstation within the second half of the study.

Other: Workplace consisting of two height-adjustable desks

Novel workplace - second half

EXPERIMENTAL

Intervention: A novel two-desk sit-to-stand workstation for 23 weeks; provided within the second half of the study. Traditional workstation within the frist half of the study.

Other: Workplace consisting of two height-adjustable desks

Control group

NO INTERVENTION

Control group subjects did not encounter any changes in their regular office environments. Traditional workstation for both halves of the study.

Interventions

Desk arrangements: self-determined by the participants Desk equipment: depending on pre-intervention condition - 1 or 2 screens per desk Build-up: one day prior to the intervention period at the location of the workplace Adjustment: together with the study leader

Novel workplace - first halfNovel workplace - second half

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy Caucasian (no acute or chronic diseases)
  • Normal weight or slightly overweight (BMI: 18.5 - 27.5 kg/m²)
  • Regularly working in sedentary office environments
  • Regular computer users
  • Fluent German speakers
  • Consented to participate

You may not qualify if:

  • Heavily overweight \& Obesity (BMI \> 27.5 kg/m²)
  • Short office stay duration (\< 8 h / day or \< 20 h / week)
  • Experience in sit-to-stand workstations
  • Acute or chronic diseases
  • Inability to stand
  • Visual impairments that had not been corrected
  • Color blindness
  • People planning to change their physical activity level
  • Regular smokers (\> 1 cigarette /day)
  • Not consented to participate

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Applied Sciences Upper Austria

Linz, Upper Austria, 4020, Austria

Location

Related Publications (11)

  • Neuhaus M, Healy GN, Dunstan DW, Owen N, Eakin EG. Workplace sitting and height-adjustable workstations: a randomized controlled trial. Am J Prev Med. 2014 Jan;46(1):30-40. doi: 10.1016/j.amepre.2013.09.009.

    PMID: 24355669BACKGROUND
  • Commissaris DA, Konemann R, Hiemstra-van Mastrigt S, Burford EM, Botter J, Douwes M, Ellegast RP. Effects of a standing and three dynamic workstations on computer task performance and cognitive function tests. Appl Ergon. 2014 Nov;45(6):1570-8. doi: 10.1016/j.apergo.2014.05.003. Epub 2014 Jun 17.

    PMID: 24951234BACKGROUND
  • Bates ME, Lemay EP Jr. The d2 Test of attention: construct validity and extensions in scoring techniques. J Int Neuropsychol Soc. 2004 May;10(3):392-400. doi: 10.1017/S135561770410307X.

    PMID: 15147597BACKGROUND
  • Best JR, Nagamatsu LS, Liu-Ambrose T. Improvements to executive function during exercise training predict maintenance of physical activity over the following year. Front Hum Neurosci. 2014 May 27;8:353. doi: 10.3389/fnhum.2014.00353. eCollection 2014.

    PMID: 24904387BACKGROUND
  • Hennig J, Friebe J, Ryl I, Kramer B, Bottcher J, Netter P. Upright posture influences salivary cortisol. Psychoneuroendocrinology. 2000 Jan;25(1):69-83. doi: 10.1016/s0306-4530(99)00037-2.

    PMID: 10633536BACKGROUND
  • Van der Elst W, Van Boxtel MP, Van Breukelen GJ, Jolles J. The Stroop color-word test: influence of age, sex, and education; and normative data for a large sample across the adult age range. Assessment. 2006 Mar;13(1):62-79. doi: 10.1177/1073191105283427.

    PMID: 16443719BACKGROUND
  • Lynch BM. Sedentary behavior and cancer: a systematic review of the literature and proposed biological mechanisms. Cancer Epidemiol Biomarkers Prev. 2010 Nov;19(11):2691-709. doi: 10.1158/1055-9965.EPI-10-0815. Epub 2010 Sep 10.

    PMID: 20833969BACKGROUND
  • Owen N, Sparling PB, Healy GN, Dunstan DW, Matthews CE. Sedentary behavior: emerging evidence for a new health risk. Mayo Clin Proc. 2010 Dec;85(12):1138-41. doi: 10.4065/mcp.2010.0444. No abstract available.

    PMID: 21123641BACKGROUND
  • Brown WJ, Miller YD, Miller R. Sitting time and work patterns as indicators of overweight and obesity in Australian adults. Int J Obes Relat Metab Disord. 2003 Nov;27(11):1340-6. doi: 10.1038/sj.ijo.0802426.

    PMID: 14574344BACKGROUND
  • Schwartz B, Kapellusch JM, Baca A, Wessner B. Medium-term effects of a two-desk sit/stand workstation on cognitive performance and workload for healthy people performing sedentary work: a secondary analysis of a randomised controlled trial. Ergonomics. 2019 Jun;62(6):794-810. doi: 10.1080/00140139.2019.1577497. Epub 2019 Apr 7.

  • Schwartz B, Kapellusch JM, Schrempf A, Probst K, Haller M, Baca A. Effect of a novel two-desk sit-to-stand workplace (ACTIVE OFFICE) on sitting time, performance and physiological parameters: protocol for a randomized control trial. BMC Public Health. 2016 Jul 15;16:578. doi: 10.1186/s12889-016-3271-y.

MeSH Terms

Conditions

Sedentary Behavior

Condition Hierarchy (Ancestors)

Behavior

Study Officials

  • Bernhard Schwartz, MSc

    University of Applied Sciences Upper Austria

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Research Associate

Study Record Dates

First Submitted

July 4, 2016

First Posted

July 7, 2016

Study Start

January 1, 2014

Primary Completion

March 1, 2015

Study Completion

March 1, 2015

Last Updated

July 15, 2016

Record last verified: 2016-07

Data Sharing

IPD Sharing
Will share

Data resulting from this study will be analyzed and published in the PIs' PhD-thesis and journal articles.

Locations