NCT02823119

Brief Summary

The aim of this study is to evaluate the effect of hysteroscope diameter on the pain experienced by nulliparous patients undergoing diagnostic office hysteroscopy.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for phase_2 pain

Timeline
Completed

Started Aug 2016

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 7, 2016

Completed
29 days until next milestone

First Posted

Study publicly available on registry

July 6, 2016

Completed
26 days until next milestone

Study Start

First participant enrolled

August 1, 2016

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2017

Completed
Last Updated

July 6, 2016

Status Verified

June 1, 2016

Enrollment Period

10 months

First QC Date

June 7, 2016

Last Update Submit

June 30, 2016

Conditions

Keywords

Mini-hysteroscopyOffice hysteroscopyPain

Outcome Measures

Primary Outcomes (1)

  • Intensity of pain

    Intensity of pain assessed by the Visual Analog Scale (VAS)"

    up to 30 minutes

Secondary Outcomes (1)

  • Duration of procedure

    intraoperative

Study Arms (2)

Mini-hysteroscopy

EXPERIMENTAL

A rigid 2.7-mm hysteroscope with a 30° forward oblique lens and an outer sheath diameter of 3.3 mm.

Device: Mini-hysteroscopy

Conventional Office Hysteroscopy

ACTIVE COMPARATOR

A rigid 2.9-mm hysteroscope with a 30° forward oblique lens and an outer sheath diameter of 5 mm

Device: Conventional Office Hysteroscopy

Interventions

Hysteroscopy will be performed with the use of the non-touch technique (vaginoscopic approach). The investigators will use a rigid 2.7-mm hysteroscope with a 30° forward oblique lens and an outer sheath diameter of 3.3 mm. All of the procedures will be diagnostic.

Mini-hysteroscopy

. Hysteroscopy will be performed with the use of the non-touch technique (vaginoscopic approach). The investigators will use a rigid 2.9-mm hysteroscope with a 30° forward oblique lens and an outer sheath diameter of 5 mm. All of the procedures will be diagnostic.

Conventional Office Hysteroscopy

Eligibility Criteria

Age18 Years - 45 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Nulliparous patients

You may not qualify if:

  • Parous patients, menopausal status, cervical pathology, and previous cervical surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Obstetrics and Gynecology Department,Cairo university

Cairo, Egypt

Location

Related Publications (1)

  • Rullo S, Sorrenti G, Marziali M, Ermini B, Sesti F, Piccione E. Office hysteroscopy: comparison of 2.7- and 4-mm hysteroscopes for acceptability, feasibility and diagnostic accuracy. J Reprod Med. 2005 Jan;50(1):45-8.

    PMID: 15730173BACKGROUND

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Usama M Fouda, M.D, PhD

    Cairo University

    STUDY DIRECTOR

Central Study Contacts

Usama M Fouda, M.D, PhD

CONTACT

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
M.D, PhD

Study Record Dates

First Submitted

June 7, 2016

First Posted

July 6, 2016

Study Start

August 1, 2016

Primary Completion

June 1, 2017

Study Completion

June 1, 2017

Last Updated

July 6, 2016

Record last verified: 2016-06

Locations