Twitter-enabled Mobile Messaging for Smoking Relapse Prevention (Tweet2Quit)
Tweet2Quit
Social Media Technology for Treating Tobacco Addiction
2 other identifiers
interventional
980
1 country
2
Brief Summary
Tweet2Quit is an innovative smoking cessation intervention that combines real-time online peer-to-peer support with auto messaging. In a three-group randomized controlled trial, the investigators will compare: 1) usual care, 2) Tweet2Quit-coed, and 3) Tweet2Quit-Women only.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for phase_2
Started Oct 2016
Longer than P75 for phase_2
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 16, 2016
CompletedFirst Posted
Study publicly available on registry
July 6, 2016
CompletedStudy Start
First participant enrolled
October 1, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2022
CompletedResults Posted
Study results publicly available
November 21, 2024
CompletedNovember 21, 2024
November 1, 2024
5.9 years
June 16, 2016
August 24, 2024
November 14, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Percentage of Participants With a 6-month Sustained Abstinence
Percentage of participants who reported no use of tobacco products by answering the questions: 'How many cigarettes have you smoked', 'How many other tobacco products have you used', and 'How many times have you used e-cigs' since the quit date (assessed at 1, 3 and 6 months post quit date) confirmed by salivary cotinine measurement (assessed at 3 and 6 months post quit date). Note: We will apply the Russell Standard for abstinence, allowing 5 or fewer instances of tobacco use over 6 months. In our primary (most rigorous) analysis, we will consider a cotinine-positive test, regardless of source, to be non-abstinent. In additional analyses, we will code as abstinent those who assert tobacco abstinence but continue use of FDA-approved nicotine replacement therapy. In other analyses we will report results with ENDS-only users coded first as non-abstinent and then for comparison as abstinent.
6 Month
Study Arms (4)
NRT + Web Guide
ACTIVE COMPARATORNCI Smokefree.gov plus 8 weeks of combination NRT (nicotine patch plus gum/lozenges)
NRT + Web Guide + Tweet2Quit-Coed
EXPERIMENTALNCI Smokefree.gov plus 8 weeks of combination NRT (nicotine patch plus gum/lozenges) plus assignment to a coed Tweet2Quit group
NRT + Web Guide + Tweet2Quit-Women
EXPERIMENTALExperimental: NRT + Web Guide + Tweet2Quit-Women NCI Smokefree.gov plus 8 weeks of combination NRT (nicotine patch plus gum/lozenges) plus assignment to a women-only Tweet2Quit group
Initial Pilot Group (NRT + Web Guide + Tweet2Quit-Coed)
OTHERThe initial pilot group was run to check technology functionality and user acceptance; it was not included in outcome assessments. These participants received NCI Smokefree.gov plus 8 weeks of combination NRT (nicotine patch plus gum/lozenges) plus assignment to a coed Tweet2Quit group.
Interventions
8-weeks of study provided NRT patch, and 8-weeks of study provided NRT gum of varying strengths or 8-weeks of study provided NRT lozenges, depending on patient level of nicotine dependence.
A website that will provide participants with access to an evidence-based set of "base" treatment materials in one central location. The site will include information on the proper use of nicotine patches, gum, lozenges, and it will have a direct link for participants to access the NCI's Smokefree.gov Quit Guide. The website will remind participants about quit dates and send alerts via email to participants to complete the appropriate NCI Quit Guide modules.
A fully automated, 90-day quit smoking intervention that provides an online, peer-to-peer support group for quitting and uses twice-daily automessages to encourage and direct the peer-to-peer exchanges. Each group will consist of 12 buddy pairs (matched on key demographics) that will be introduced via automated texts. The program will generate twice-daily programmed contacts (e.g., "what benefits do you hope to get from quitting smoking?"). Automated pattern detection software will identify and address any problematic low tweeting within a group.
Eligibility Criteria
You may qualify if:
- Are 21-59 years of age
- Are smoking 5+ cigarettes/day and 100+ cigarettes in one's lifetime
- In the preparation stage of quitting smoking
- Are English speaking
- Have a mobile phone with an unlimited texting plan and internet access (via mobile phone)
- Text at least once a week
- Are a social media user
- Have an active email account
- Lives in the continental USA
You may not qualify if:
- Have certain medical conditions that are contraindicated for nicotine replacement therapy: pregnant, breast feeding, a recent heart attack, an irregular heartbeat, high blood pressure not controlled with medication, skin allergies to adhesive tape or serious skin problems, taking a prescription medicine for depression, and/or any other medical conditions that would prevent you from completing this study.
- Are an illicit hard drug user or regular marijuana user
- Share a household with someone else or has an immediate family member who has already enrolled in the study currently or in the past or if the participant has already been enrolled or failed to pass the screening once already since October 2016
- Participated in Tweet2Quit between 2012-2013 in a Twitter group and was not an active tweeter (\<1 week)
- Fails to provide valid forms of all the required personal contact information
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of California, Irvinelead
- Stanford Universitycollaborator
- National Cancer Institute (NCI)collaborator
Study Sites (2)
University of California, Irvine - Paul Merage School of Business
Irvine, California, 92697, United States
Stanford University School of Medicine
Stanford, California, 94305, United States
Related Publications (2)
Pechmann C, Phillips C, Calder D, Prochaska JJ. Facebook Recruitment Using Zip Codes to Improve Diversity in Health Research: Longitudinal Observational Study. J Med Internet Res. 2020 Jun 5;22(6):e17554. doi: 10.2196/17554.
PMID: 32501274DERIVEDPechmann CA, Calder D, Phillips C, Delucchi K, Prochaska JJ. The Use of Web-Based Support Groups Versus Usual Quit-Smoking Care for Men and Women Aged 21-59 Years: Protocol for a Randomized Controlled Trial. JMIR Res Protoc. 2020 Jan 14;9(1):e16417. doi: 10.2196/16417.
PMID: 31934869DERIVED
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Results Point of Contact
- Title
- Professor Cornelia Pechmann
- Organization
- University of California Irvine
Study Officials
- PRINCIPAL INVESTIGATOR
Connie (Cornelia) Pechmann, PhD, MBA, MS
University of California, Irvine
- PRINCIPAL INVESTIGATOR
Judith J Prochaska, PhD, MPH
Stanford University
Publication Agreements
- PI is Sponsor Employee
- Yes
Study Design
- Study Type
- interventional
- Phase
- phase 2
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principle Investigator
Study Record Dates
First Submitted
June 16, 2016
First Posted
July 6, 2016
Study Start
October 1, 2016
Primary Completion
September 1, 2022
Study Completion
September 1, 2022
Last Updated
November 21, 2024
Results First Posted
November 21, 2024
Record last verified: 2024-11
Data Sharing
- IPD Sharing
- Will not share