Biomechanics Research in the Effects of Interactive Dynamic Balance Training on Postural and Gait Control in Older Adults

NCT02821091 | Terminated

• 1 other identifier: 201501039RINC
• Study Type: interventional
• Target: 27
• Locations: 1 country
• Sites: 1

Brief Summary

Aim 1: Determine the relationships between muscle quality and balance performance as well as any association with fracture and fall history in older adults. Muscle quality will be calculated from the information of muscle strength and body composition (strength/lean muscle mass). The investigators will compute the joint torque during functional activates using biomechanical data from the 3-D motion analysis, whereas the lean skeletal muscle mass will be determined by the bioelectrical impedance analysis (BIA). Clinical and functional assessments for balance performance will also be conducted. Fracture and fall history prior to the testing will be recorded retrospectively. Aim 2: Identify the relationships between force usages during balance perturbation in older adults. Lateral and forward/backward perturbation while walking will be used to elicit balance recovery responses. The degree of necessary joint force and how this relates to a person's functional capacity at specific joint levels will be determined by the torque demand to capacity ratio (DCR: task demands relative to strength capacity). The DCR provides a joint-specific unified scalar quantity representing the balance recovery demand normalized by the maximum muscle strength capacity of an individual. It would indicate whether a person can recover balance and to what extent of his/her maximum capacity is taxed. Aim 3: Examine the effectiveness and long-term effects of a novel 2-month personalized strengthening and balance training program on improving balance performance in older adults. Personalized strengthening and balance training exercise will be personalized based on the results of biomechanical assessments, using the Modular Interactive Tiles System (MITS) and split-belt balance perturbation instrumented treadmill. The exercise group will receive training 2 times a week for 2 months and the age-matched control group will maintain their usual daily life activities. All assessments will be performed at baseline, and 1 week after training. Follow-up telephone interviews will be conducted at 6, 9, and 12 months following the training period.

Conditions

Older Adults, Balance

Outcome Measures

Primary Outcomes (1)

• Timed Up and Go Test

  Up to 52 weeks

Study Arms (3)

Control young adults

NO INTERVENTION

Healthy adults, age between 20 to 59 yeas old

Control old adults

NO INTERVENTION

Healthy adults, age between 60 to 80 yeas old

Exercise old adults

EXPERIMENTAL

Healthy adults, age between 60 to 80 yeas old received interactive dynamic balance training

Other: Interactive Dynamic Balance Training

Interventions

Interactive Dynamic Balance Training OTHER

Exercise old adults

Eligibility Criteria

• Age: 20 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• For control young adults group:
• able to stand and walk for 5 minutes independently without assistant
• aging between 20 and 59 years old
• For older adults group:
• able to stand and walk for 5 minutes independently without assistant
• aging between 60 and 80 years old;

You may not qualify if:

• pre-existing major lower-extremity pathology (e.g., Chronic ankle instability or severe osteoarthritis)
• neurological disorders or balance difficulties (e.g., Vertigo, poor vision, dizziness, stroke, or epilepsy) that would prevent standing for the duration of the testing procedures without the aid of an assistive device
• health conditions (e.g., Heart disease, uncontrolled hypertension, chronic obstructive pulmonary diseases) that would exclude participation in a balance exercise program.

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

National Taiwan University Hospital

Taipei, Taiwan

Location

Study Officials

• Wei-Li Hsu

  National Taiwan University Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 29, 2016
• First Posted: July 1, 2016
• Study Start: April 16, 2015
• Primary Completion: April 26, 2016
• Study Completion: January 24, 2017
• Last Updated: May 8, 2017

Record last verified: 2016-06

Locations

TW (1)