NCT02821078

Brief Summary

The objective of the project is to establish the 3D velocity mapping of the hepatic vasculature and its consistency

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
44

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2017

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 29, 2016

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 1, 2016

Completed
9 months until next milestone

Study Start

First participant enrolled

March 16, 2017

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 24, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 24, 2019

Completed
Last Updated

November 19, 2025

Status Verified

November 1, 2025

Enrollment Period

1.9 years

First QC Date

June 29, 2016

Last Update Submit

November 17, 2025

Conditions

Magnetic Resonance Imaging

Keywords

phase-contrast MRIblood flowvelocity mappingabdominal imagingQuantitative MRI

Outcome Measures

Primary Outcomes (1)

  • Hepatic blood flow difference

    difference between (hepatic artery + portal vein flows) and inferior vena cava differential flow (infra and supra hepatic)

    Day 0

Secondary Outcomes (1)

  • Comparison between 4D and 2D flow

    Day 0

Study Arms (1)

Participants

EXPERIMENTAL

In addition to the standard clinical MR protocol, 2 added sequences: * 4D flow imaging sequence * standard 2D-PhaseContrast at portal trunk level as reference

Other: 4D flow imaging sequence

Interventions

4D flow imaging sequenceOTHER

4D flow imaging sequence

Participants

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Participants have fasted for 6 hours before examination
  • Adult participants

You may not qualify if:

  • Anyone with a classic contraindication to MRI
  • Recanalized umbilical vein
  • Severe obesity
  • Gadolinium chelate allergy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU Amiens

Amiens, 80054, France

Location

Related Publications (1)

  • Yzet T, Bouzerar R, Baledent O, Renard C, Lumbala DM, Nguyen-Khac E, Regimbeau JM, Deramond H, Meyer ME. Dynamic measurements of total hepatic blood flow with Phase Contrast MRI. Eur J Radiol. 2010 Jan;73(1):119-24. doi: 10.1016/j.ejrad.2008.09.032. Epub 2008 Nov 12.

    PMID: 19008062RESULT

Study Officials

  • Thierry Yzet, MD, PhD

    CHU Amiens

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 29, 2016

First Posted

July 1, 2016

Study Start

March 16, 2017

Primary Completion

January 24, 2019

Study Completion

January 24, 2019

Last Updated

November 19, 2025

Record last verified: 2025-11

Data Sharing

IPD Sharing
Will not share

Locations

FR(1)