Influence of Couch Tracking Motion

NCT02820532 | Completed

• 1 other identifier: 2016-00163
• Study Type: interventional
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Tumor motion increases the uncertainty in Radiation Oncology. Couch tracking can compensate for this uncertainty. However it is not known if the couch motion influences the respiratory pattern of the patients. This will be evaluated in this study on healthy volunteers.

Conditions

Respiratory Amplitude

Outcome Measures

Primary Outcomes (1)

• Respiratory amplitude

  Change of respiratory motion due to couch motion. Respiration will be measured on the chest wall using a contact-free measurement.

  baseline and 20 min

Secondary Outcomes (5)

• Heart beat

  baseline and 20 min

• Skin humidity

  baseline and 20 min

• Pupil motion

  baseline and 20 min

• Body motion

  baseline and 20 min

• Motion sickness

  baseline and 20 min

Study Arms (1)

Tracking

OTHER

The volunteers will be placed on the treatment couch. Their respiratory motion will be measured and the treatment couch will be moved accordingly. During the couch motion experiment the heartbeat, the skin humidity, the respiratory characteristics and the pupil motion will be additionally measured.

Device: Protura Treatment table

Interventions

Protura Treatment table DEVICE

The treatment couch will be moved according to the respiratory motion of the patient. As a reference first the respiration will be measured without couch motion, than the couch will be switched on and we will evaluate if the respiration changes due to the motion of the couch. This procedure will be repeated once.

Tracking

Eligibility Criteria

• Age: 18 Years - 100 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Healthy volunteers
• Male and Female subjects
• ≥18 and ≤100 years
• Written informed consent by the participant after information about the project
• German speaking

You may not qualify if:

• Known or suspected non-compliance, drug or alcohol abuse,
• Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant,
• Body weight exceeding 200kg

Sponsors & Collaborators

• University of Zurich: lead
• Technical University Zurich: collaborator

Study Sites (1)

University Hospital Zurich

Zurich, 8091, Switzerland

Location

Related Publications (2)

• Johl A, Bogowicz M, Ehrbar S, Guckenberger M, Klock S, Meboldt M, Riesterer O, Zeilinger M, Schmid Daners M, Tanadini-Lang S. Body motion during dynamic couch tracking with healthy volunteers. Phys Med Biol. 2018 Dec 19;64(1):015001. doi: 10.1088/1361-6560/aaf361.

  PMID: 30523943 DERIVED

• Johl A, Bogowicz M, Ehrbar S, Guckenberger M, Klock S, Meboldt M, Riesterer O, Zeilinger M, Schmid Daners M, Tanadini-Lang S. Unconscious physiological response of healthy volunteers to dynamic respiration-synchronized couch motion. Radiat Oncol. 2017 Nov 28;12(1):189. doi: 10.1186/s13014-017-0925-6.

  PMID: 29183337 DERIVED

Study Officials

• Matthias Guckenberger, MD

  University Hospital Zurich, Department of Radiation Oncology

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 20, 2016
• First Posted: July 1, 2016
• Study Start: July 1, 2016
• Primary Completion: April 1, 2018
• Study Completion: April 1, 2018
• Last Updated: May 8, 2018

Record last verified: 2018-05

Locations

CH (1)