Persona of Central Serous Chorioretinopathy

NCT02819622 | Completed

• 1 other identifier: INV-2014-204
• Study Type: observational
• Target: 83
• Locations: 1 country
• Sites: 1

Brief Summary

Purpose: Central serous retinopathy (CSCR) is characterized by macular detachment due to thickened choroid mostly affecting young men under perceived stress. While most previous studies in CSCR have been retrospective and have focused on a single facet of the patient's personality, the investigators conducted a prospective intercontinental controlled study to analyze the multifaceted personality profile in CSCR. Design: Prospective interview. Participants and Controls: Subjects with CSCR consented to participate in a questionnaire. Controls not having retinal disease were recruited from the same clinic. Main Outcome Measures: The main parameters registered were presence of stress, daily number of cups caffeine intake, personality traits (Type A; obsessive-compulsive; aggressive). Methods: The interview consisted of a 60-item questionnaire. Recruitment of participants was from January 2015 to February 2016. Controls were matched for age, gender and race. Statistical analyses were done using univariate and multivariate analysis.

Conditions

Personality Type

Outcome Measures

Primary Outcomes (1)

• personality type

  one interview by the ophthalmologist himself

  through study completion, an average of 1 year

Study Arms (2)

Control group

control (no disease)

central serous retinopathy group

Central serous retinopathy (with CSCR disease) by exam and OCT

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients with central serous retinopathy

You may qualify if:

• clinical evidence by fluorescein angiography and OCT of CSCR disease
• willingness to undergo long interview
• ability to sign an informed consent

You may not qualify if:

• severe systemic hypertension
• eclampsia

Sponsors & Collaborators

• Rafic Hariri University Hospital: lead

Study Sites (1)

Rafic Hariri University Hospital

Beirut, South Beirut, 1136044, Lebanon

Location

Related Publications (4)

• Liu B, Deng T, Zhang J. RISK FACTORS FOR CENTRAL SEROUS CHORIORETINOPATHY: A Systematic Review and Meta-Analysis. Retina. 2016 Jan;36(1):9-19. doi: 10.1097/IAE.0000000000000837.

  PMID: 26710181 BACKGROUND

• Daruich A, Matet A, Dirani A, Bousquet E, Zhao M, Farman N, Jaisser F, Behar-Cohen F. Central serous chorioretinopathy: Recent findings and new physiopathology hypothesis. Prog Retin Eye Res. 2015 Sep;48:82-118. doi: 10.1016/j.preteyeres.2015.05.003. Epub 2015 May 27.

  PMID: 26026923 BACKGROUND

• Sacca SC, Vagge A, Pulliero A, Izzotti A. Helicobacter pylori infection and eye diseases: a systematic review. Medicine (Baltimore). 2014 Dec;93(28):e216. doi: 10.1097/MD.0000000000000216.

  PMID: 25526440 BACKGROUND

• Mateo-Montoya A, Mauget-Fayse M. Helicobacter pylori as a risk factor for central serous chorioretinopathy: Literature review. World J Gastrointest Pathophysiol. 2014 Aug 15;5(3):355-8. doi: 10.4291/wjgp.v5.i3.355.

  PMID: 25133035 BACKGROUND

Study Officials

• ahmad mansour, md

  RHUH

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Chair, Department of Opthalmology, Rafic Hariri Hospital

Study Record Dates

• First Submitted: June 14, 2016
• First Posted: June 30, 2016
• Study Start: January 1, 2015
• Primary Completion: February 1, 2016
• Study Completion: February 1, 2016
• Last Updated: June 30, 2016

Record last verified: 2016-06

Data Sharing

• IPD Sharing: Will share

Locations

LE (1)