NCT02818634

Brief Summary

The purpose of this study was to investigate the effect of 'muscle sparing technique' while harvesting costal/rib cartilage on postoperative donor-site morbidity -namely postoperative pain. Although authors report 'muscle sparing technique' cause less pain its not investigated in an evidence-based-medicine perspective. Therefore the investigators are planning a controlled, prospective clinical trial to compare the conventional method and 'muscle sparing technique'. Effect of Costal Harvesting Technique on Postoperative Donor-site Morbidity: Does Muscle Sparing Technique Cause Less Postoperative Pain ? A Clinical Trial

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2016

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2016

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

June 17, 2016

Completed
13 days until next milestone

First Posted

Study publicly available on registry

June 30, 2016

Completed
1 day until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2016

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2016

Completed
Last Updated

June 30, 2016

Status Verified

June 1, 2016

Enrollment Period

5 months

First QC Date

June 17, 2016

Last Update Submit

June 27, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in Postoperative Pain

    Postoperative pain and its change from baseline to 45th postoperative day will be evaluated with Visual Analogue Scale

    Postoperative first 45 days

Study Arms (2)

Muscle-sparing

ACTIVE COMPARATOR

Following skin incision with No.15 blade; all layers including the subcutaneous fat, muscle fascia and muscles covering the cartilage were passed with blunt dissection. Muscle fibers were dissected parallel to their positioning.

Procedure: Harvesting rib cartilage

Muscle-cutting

ACTIVE COMPARATOR

Following skin incision with No.15 blade; all layers including the subcutaneous fat, muscle fascia and muscles covering the cartilage were cut with Monopolar electrocautery at (25 watts).

Procedure: Harvesting rib cartilage

Interventions

Muscle-cuttingMuscle-sparing

Eligibility Criteria

Age17 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Revision rhinoplasty
  • when costal cartilage is harvested full-thickness

You may not qualify if:

  • Fibromyalgia
  • No consent
  • When patient does not comply with follow-up

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Gaziosmanpasa Taksim Research and Education Hospital, Department of Otorhinolaryngology

Istanbul, Gaziosmanpasa, 00000, Turkey (Türkiye)

RECRUITING

Related Publications (2)

  • Fedok FG. Costal Cartilage Grafts in Rhinoplasty. Clin Plast Surg. 2016 Jan;43(1):201-12. doi: 10.1016/j.cps.2015.08.002. Epub 2015 Oct 24.

    PMID: 26616708BACKGROUND
  • Cochran CS. Harvesting Rib Cartilage in Primary and Secondary Rhinoplasty. Clin Plast Surg. 2016 Jan;43(1):195-200. doi: 10.1016/j.cps.2015.09.018. Epub 2015 Oct 23.

    PMID: 26616707BACKGROUND

Study Officials

  • Berke Ozucer, MD

    Gaziosmanpasa Taksim Research and Education Hospital, Otorhinolaryngology Deparment

    STUDY DIRECTOR
  • Mehmet E Dinc, MD

    Gaziosmanpasa Taksim Research and Education Hospital, Otorhinolaryngology Deparment

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Berke Ozucer, MD

CONTACT

Mehmet E Dinc, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, Otolaryngologist

Study Record Dates

First Submitted

June 17, 2016

First Posted

June 30, 2016

Study Start

February 1, 2016

Primary Completion

July 1, 2016

Study Completion

August 1, 2016

Last Updated

June 30, 2016

Record last verified: 2016-06

Locations