NCT02812173

Brief Summary

The purpose of the study is to determine, whether the postoperative quality of micturition and continence can be improved depending on the urinary drainage catheter and retention after robot assisted radical prostatectomy. Another finding could be the study of the pain assessment of the patient, as well as the pain medication at the various derivatives. Further check whether infections and the presence of bacteriuria can be reduced or avoided by the form of urinary drainage.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
234

participants targeted

Target at P75+ for not_applicable prostate-cancer

Timeline
Completed

Started May 2016

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2016

Completed
17 days until next milestone

First Submitted

Initial submission to the registry

May 18, 2016

Completed
1 month until next milestone

First Posted

Study publicly available on registry

June 24, 2016

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2017

Completed
11 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2018

Completed
Last Updated

December 7, 2022

Status Verified

December 1, 2022

Enrollment Period

1.2 years

First QC Date

May 18, 2016

Last Update Submit

December 6, 2022

Conditions

Keywords

urinary drainageurethral cathetersuprapubic tubepaindiscomfortradical prostatectomyrobotic surgeryurinary infection

Outcome Measures

Primary Outcomes (1)

  • Urinary leakage measured by pad test in grams

    within the day 2 or day 5 after the surgery for 24 hours

Secondary Outcomes (4)

  • Detection of postoperative pain related to urinary drainage by numeric rating scale (NRS)

    once a day, first 7 days after the surgery

  • Recording of complications

    within the 4 weeks after surgery

  • Urine status measured by flow cytometry

    within the day 2 or day 5 after the surgery

  • Residual urine measured by bladder scan in ml

    3 times within the day 2 or day 5 after the surgery

Study Arms (3)

suprapubic tube ex 2 day

ACTIVE COMPARATOR

patients who underwent robot-assisted radical prostatectomy and got intraoperatively, a suprapubic tube, which was withdrawn on the 2th day after the surgery

Device: suprapubic tube ex 2 day

suprapubic tube ex 5 day

ACTIVE COMPARATOR

patients who underwent robot-assisted radical prostatectomy and got intraoperatively, a suprapubic tube, which was withdrawn on the 5th day after the surgery

Device: suprapubic tube ex 5 day

transurethral catheter ex 5 day

ACTIVE COMPARATOR

patients who underwent robot-assisted radical prostatectomy and got intraoperatively, a transurethral catheter, which was withdrawn on the 5th day after the surgery

Device: transurethral catheter ex 5 day

Interventions

balloon catheter for suprapubic bladder-drainage, suprapubic tube removal on the second day after the surgery

Also known as: Uromed
suprapubic tube ex 2 day

balloon catheter for suprapubic bladder-drainage, suprapubic tube removal on the fifth day after the surgery

Also known as: Uromed
suprapubic tube ex 5 day

transurethral catheter withdrawal removal on the fifth day after the surgery

Also known as: Uromed
transurethral catheter ex 5 day

Eligibility Criteria

Age18 Years+
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Minimum age of 18 Years
  • Voluntarily agreement to participate in this study
  • filled in and signed Informed Consent
  • release of medical records for regulatory or research purposes
  • clinically organ-confined prostate cancer
  • recommended and planned robot-assisted radical prostatectomy

You may not qualify if:

  • Participation in other interventional trials that could interfere with the present study
  • International Prostate Symptom Score (IPPS) \> 18
  • History of radiation or chemotherapy
  • History of transurethral prostate resection
  • unable to provide informed consent
  • unwillingness to storage and forwarding of pseudonymous data

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Urology, Pediatric Urology and Urologic Oncology, St. Antonius Hospital Gronau

Gronau, 48599, Germany

Location

MeSH Terms

Conditions

Prostatic NeoplasmsPainUrinary Tract Infections

Condition Hierarchy (Ancestors)

Genital Neoplasms, MaleUrogenital NeoplasmsNeoplasms by SiteNeoplasmsGenital Diseases, MaleGenital DiseasesUrogenital DiseasesProstatic DiseasesMale Urogenital DiseasesNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsInfectionsUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy Complications

Study Officials

  • Nina Harke, MD.

    St. Antonius Hospital Gronau

    PRINCIPAL INVESTIGATOR
  • Mustapha Addali, MD.

    St. Antonius Hospital Gronau

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 18, 2016

First Posted

June 24, 2016

Study Start

May 1, 2016

Primary Completion

July 1, 2017

Study Completion

June 1, 2018

Last Updated

December 7, 2022

Record last verified: 2022-12

Data Sharing

IPD Sharing
Will not share

Locations