Application of DCE-MRI in the Diagnosis of Brucellar Spondylitis

NCT02809625 | Unknown DMC

• 1 other identifier: AHInnerMongolia
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Brucellosis, also known as Mediterranean fever, undulant fever, or Malta fever is a zoonotic disease caused by Brucella infection.With the rapid development of animal husbandry and aquaculture and increasing consumption of dairy products in urban residents, the incidence of this disease in Inner Mongolia and even in the mainland area of China is significantly increased. The disease can damage multiple systems including nervous system, circulatory system, reproductive system and bone joints, etc. The sooner the diagnosis of brucellar spondylitis is diagnosed and treated, the better will be the prognosis of the patients which can prevent the development of severe complications and diminish the need for surgical therapy. Thus the early diagnosis of brucellar spondylitis was of great significance.We quantitatively analyzed the brucellar spondylitis with DCE-MRI to explore the application of DCE-MRI in the early diagnosis of brucellar spondylitis.

Conditions

Brucella Spondylitis

Keywords

Dynamic contrast -enhanced MRI; brucella spondylitis

Outcome Measures

Primary Outcomes (1)

• The useful value of dynamic contrast-enhanced MRI in clinical diagnosis and early diagnosis of brucella spondylitis

  2 years

Eligibility Criteria

• Age: 35 Years - 62 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

About 100 patients with Brucellosis including patients with brucella spondylitis obviously and patients with obvious waist pain but the conventional MRI showed no obvious abnormalities were selected.

You may qualify if:

• The epidemiological exposure history of different extents, accompanied with symptoms including
• low fever
• night sweats
• intermittent lower back pain
• movement limitation

You may not qualify if:

• With other disease like tuberculous spondylitis,vertebral metastases,etc

Sponsors & Collaborators

• The Affiliated Hospital of Inner Mongolia Medical University: lead
• National Natural Science Foundation of China: collaborator

Study Sites (1)

The Affiliated Hospital of Inner Mongolia Medical University

Inner Mongolia, China

RECRUITING

Study Officials

• Peng fei Qiao, MD

  The Affiliated Hospital of Inner Mongolia Medical University

  STUDY DIRECTOR

Central Study Contacts

Peng fei Qiao, MD

CONTACT

+86-15904718239; qpfff@126.com

Yao Gao, PhD

CONTACT

+86-15024931010; 24853170@qq.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 16, 2016
• First Posted: June 22, 2016
• Study Start: March 1, 2016
• Primary Completion: December 1, 2023
• Study Completion: December 1, 2024
• Last Updated: July 20, 2023

Record last verified: 2023-07

Locations

CN (1)