NCT02807948

Brief Summary

This study is a prospective, non-randomized, multi-center study of subjects implanted with an SJM pacemakers, implantable cardioverter defibrillator (ICD), and cardiac resynchronization therapy (CRT) devices who are clinically indicated for a non-thoracic MRI scan.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
189

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jun 2016

Geographic Reach
1 country

58 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2016

Completed
16 days until next milestone

First Submitted

Initial submission to the registry

June 17, 2016

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 21, 2016

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2017

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

January 31, 2018

Completed
1.6 years until next milestone

Results Posted

Study results publicly available

August 26, 2019

Completed
Last Updated

August 26, 2019

Status Verified

August 1, 2019

Enrollment Period

1.6 years

First QC Date

June 17, 2016

Results QC Date

August 7, 2019

Last Update Submit

August 7, 2019

Conditions

Keywords

MRI Scan, pacemakers, ICD, CRT

Outcome Measures

Primary Outcomes (2)

  • The Proportion of MRI Scans From Pacemakers or CRT-Ps Providing Sufficient Image Quality to Allow for a Diagnostic Interpretation.

    Based on the ability of the radiologist to read and provide a diagnosis/report.

    1 month

  • The Proportion of MRI Scans From ICDs or CRT-Ds Providing Sufficient Image Quality to Allow for a Diagnostic Interpretation.

    Based on the ability of the radiologist to read and provide a diagnosis/report.

    1 month

Study Arms (1)

Pacemaker, ICD, or CRT device patients

OTHER

Subjects who need a non-thoracic clinically indicated scan

Device: Pacemaker, ICD, or CRT device

Interventions

MRI Scans on SJM device implanted subjects for clinical purpose

Pacemaker, ICD, or CRT device patients

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient is implanted with a market-released St. Jude Medical pacemaker, ICD, or CRT current generation device listed in the study protocol and any market-released pacing or defibrillation lead.
  • Patient's device and all leads must be implanted for at least 6 weeks prior to the scheduled date of the MRI.
  • Patient has a clinical indication for a non-thoracic MRI scan, where MRI is the imaging modality of choice that will give adequate results to manage the patient.
  • Patient is scheduled for a non-thoracic MRI scan up to 1.5T.
  • Patient has a pacemaker, ICD, or CRT device implanted pectorally.
  • Patient has the ability to provide informed consent for study participation and be willing and able to comply with the study procedures.
  • Patient is 18 years or above, or of legal age to give informed consent specific to state and national law.

You may not qualify if:

  • Patient has an ICD/CRT-D and is pacemaker dependent
  • Capture threshold is greater than 2.5 volts at 0.5 ms for RA and RV leads
  • Pacing lead impedance is NOT within range (i.e. ≥ 200 and ≤ 2000 ohms)
  • High voltage lead impedance (HVLI) is NOT within range (i.e. ≥ 20 and ≤ 200 ohms)
  • Patient has a device generator battery voltage at elective replacement interval (ERI)
  • Patient has another existing active implanted medical device (e.g. neurostimulator, infusion pump, etc.) that has MR labeling that will not allow the MRI scans to be completed.
  • Patient has other non-MRI compatible device or material implanted
  • NOTE:
  • MRI compatible knee replacements, hip replacements, stents, etc. may be included as long as the labeling of these devices allow MRI scans conducted per this protocol
  • MRI compatible mechanical, prosthetic, and bioprosthetic heart valves may be included as long as the labeling of these devices allow for MRI scans conducted per this protocol
  • Non-removable dental implants may be included
  • Patient has a lead extender, adaptor, or capped/abandoned lead
  • Patient is pregnant

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (58)

Scottsdale Medical Imaging

Scottsdale, Arizona, 85258, United States

Location

University of Arizona

Tucson, Arizona, 85719, United States

Location

St. Bernards

Jonesboro, Arkansas, 72401, United States

Location

Quest Imaging

Bakersfield, California, 93311, United States

Location

Raymond Schaerf, MD

Burbank, California, 91505, United States

Location

John Muir Medical Center

Concord, California, 94520, United States

Location

St. Helena Hospital

Deer Park, California, 94576, United States

Location

Cardiovascular Consultants Heart Center

Fresno, California, 93720, United States

Location

Newport Diagnostic Center

Newport Beach, California, 92660, United States

Location

Pro Health Advance Imaging

North Hollywood, California, 91602, United States

Location

Eisenhower Medical Center

Rancho Mirage, California, 92270, United States

Location

St. Mary's Medical Center

San Francisco, California, 94117, United States

Location

Sansum Clinic - Santa Barbara Medical Foundation

Santa Barbara, California, 93105, United States

Location

South Denver Cardiology Associates PC

Littleton, Colorado, 80120, United States

Location

Medical Center of the Rockies

Loveland, Colorado, 80538, United States

Location

Hartford Hospital

Hartford, Connecticut, 06102, United States

Location

Christiana Hospital

Newark, Delaware, 19718, United States

Location

Cardiac Arrhythmia Services

Boca Raton, Florida, 33422, United States

Location

Jupiter Medical Center

Jupiter, Florida, 33458, United States

Location

Florida Hospital

Orlando, Florida, 32803, United States

Location

Piedmont Athens Regional Medical Center

Athens, Georgia, 30606, United States

Location

Advocate Lutheran General Hospital

Park Ridge, Illinois, 60068, United States

Location

Prairie Education and Research Cooperative

Springfield, Illinois, 62701, United States

Location

Community Heart and Vascular

Indianapolis, Indiana, 46250, United States

Location

Kansas University Medical Center

Kansas City, Kansas, 66160, United States

Location

King's Daughters Medical Center

Ashland, Kentucky, 25704, United States

Location

LSU Health Sciences Center

Shreveport, Louisiana, 71130, United States

Location

Suburban Hospital

Bethesda, Maryland, 20814, United States

Location

Washington Adventist Hospital

Takoma Park, Maryland, 20912, United States

Location

McLaren Health Care Corporation

Auburn Hills, Michigan, 48326, United States

Location

Baptist Medical Center

Jackson, Mississippi, 39202, United States

Location

Advanced Radiology

Columbia, Missouri, 65201, United States

Location

St. Luke's Hospital

Kansas City, Missouri, 64111, United States

Location

Mercy Hospital St. Louis

St Louis, Missouri, 63141, United States

Location

Kearney Regional Medical Center

Kearney, Nebraska, 68845, United States

Location

Denville Diagnostics and Open MRI LLC

Denville, New Jersey, 07834, United States

Location

Borg and Ide Imaging

Rochester, New York, 14618, United States

Location

St. Francis Hospital

Roslyn, New York, 11576, United States

Location

Novant Clinical Research Institute

Winston-Salem, North Carolina, 27103, United States

Location

The Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States

Location

Ohio State University

Columbus, Ohio, 43210, United States

Location

Samaritan Heart & Vascular Institute - Cardiology Dept.

Corvallis, Oregon, 97330, United States

Location

Oregon Medical Group

Eugene, Oregon, 97401, United States

Location

Providence St. Vincent Medical Center

Portland, Oregon, 97225, United States

Location

Lehigh Valley Hospital - 17th Street

Allentown, Pennsylvania, 19118, United States

Location

Geisinger Medical Center

Danville, Pennsylvania, 17822-2150, United States

Location

St. Mary Medical Center

Langhorne, Pennsylvania, 19047, United States

Location

Allegheny Singer Research Institute

Pittsburgh, Pennsylvania, 15212, United States

Location

Donald Guthrie Foundation for Education and Research

Sayre, Pennsylvania, 18840, United States

Location

Trident Medical Center

Charleston, South Carolina, 29406, United States

Location

Erlanger Medical Center

Chattanooga, Tennessee, 37403, United States

Location

Baylor All Saints Medical Center at Fort Worth

Fort Worth, Texas, 76104, United States

Location

East Texas Medical Center

Tyler, Texas, 75701, United States

Location

Lynchburg General Hospital

Lynchburg, Virginia, 24501, United States

Location

Sentara Norfolk General Hospital

Norfolk, Virginia, 23507, United States

Location

Overlake Hospital Medical Center

Bellevue, Washington, 98004, United States

Location

Swedish Medical Center - Heart & Vascular

Seattle, Washington, 98122, United States

Location

Aurora Medical Group

Milwaukee, Wisconsin, 53215, United States

Location

MeSH Terms

Conditions

Arrhythmias, CardiacCreatine deficiency, X-linked

Interventions

Defibrillators, Implantable

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

DefibrillatorsElectrodesElectrical Equipment and SuppliesEquipment and SuppliesElectrodes, ImplantedProstheses and Implants

Results Point of Contact

Title
Adam M.Cline, MD, MSc.- Principal Scientist
Organization
Abbott

Study Officials

  • Grant Kim

    Abbott Medical Devices

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
LTE60
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 17, 2016

First Posted

June 21, 2016

Study Start

June 1, 2016

Primary Completion

December 31, 2017

Study Completion

January 31, 2018

Last Updated

August 26, 2019

Results First Posted

August 26, 2019

Record last verified: 2019-08

Data Sharing

IPD Sharing
Will not share

Locations