NCT02807493

Brief Summary

The primary objectives of this study are to determine if the use of an Occlusal Support Device (OSD)(Mouthguard) can reduce the duration and intensity of the second stage of labor, reduce the incidence of labor complications including Caesarian Sections and improve Apgar scores in newborns

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
347

participants targeted

Target at P75+ for not_applicable pregnancy

Timeline
Completed

Started Apr 2017

Longer than P75 for not_applicable pregnancy

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 8, 2016

Completed
13 days until next milestone

First Posted

Study publicly available on registry

June 21, 2016

Completed
9 months until next milestone

Study Start

First participant enrolled

April 1, 2017

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 26, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 26, 2021

Completed
1.5 years until next milestone

Results Posted

Study results publicly available

September 21, 2022

Completed
Last Updated

September 21, 2022

Status Verified

August 1, 2022

Enrollment Period

4 years

First QC Date

June 8, 2016

Results QC Date

March 11, 2022

Last Update Submit

August 25, 2022

Conditions

Keywords

PregnancyLabor and DeliveryOcclusal Support Device

Outcome Measures

Primary Outcomes (3)

  • Stage 2 Duration of Labor

    Determine if an Occlusal Support Device (OSD) can reduce the duration of the second stage of labor

    Duration of labor

  • Number of Participants With a Cesarian Section

    Determine if an OSD can reduce the incidence of labor complications including Caesarian Sections

    Baseline

  • Average Apgar Score

    Determine if the use of an OSD can improve Apgar scores in newborns. The Apgar test is done by a doctor, midwife, or nurse. The provider examines the baby's: Breathing effort Heart rate Muscle tone Reflexes Skin color Each category is scored with 0, 1, or 2, depending on the observed condition. Higher scores are better. Scores are added for a total ranging from 0-10.

    at minute 1 and minute 5

Study Arms (2)

Occlusal Support Device

EXPERIMENTAL

Support device for women in labor

Device: Occlusal Support Device

Control

PLACEBO COMPARATOR

No device given for women in labor

Other: Control

Interventions

Bite plate

Occlusal Support Device
ControlOTHER

Control group

Control

Eligibility Criteria

Age18 Years - 40 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Nulliparous women
  • Uncomplicated pregnancy
  • Singleton pregnancy

You may not qualify if:

  • Unable to provide informed consent or comply with study protocol,
  • High risk and/or complicated pregnancy,
  • Have multiple fetuses as diagnosed by ultrasound,
  • Have extensive decay or multiple broken/missing teeth that will interfere with the fabrication of an OSD

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Minnesota

Minneapolis, Minnesota, 55455, United States

Location

Results Point of Contact

Title
James Gambucci
Organization
University of Minnesota

Study Officials

  • James E Gambucci, DDS

    University of Minnesota

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 8, 2016

First Posted

June 21, 2016

Study Start

April 1, 2017

Primary Completion

March 26, 2021

Study Completion

March 26, 2021

Last Updated

September 21, 2022

Results First Posted

September 21, 2022

Record last verified: 2022-08

Data Sharing

IPD Sharing
Will not share

Locations