Role of REM Sleep Alterations in Post Operative Delirium After Cardiac Surgery

NCT02801318 | Unknown

• 1 other identifier: DELI-SLEEP
• Study Type: interventional
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

Acute confusional states known as delirium frequently occur in Intensive Care Units (ICU), mostly after cardiac surgery, leading to serious consequences. Sleep deprivation has been described in ICU patients and is considered as a risk factor for delirium but its role is still unknown. It is therefore essential to identify whether sleep deprivation and more specifically REM sleep alterations could facilitate occurence of delirium in ICU.

Conditions

Delirium Symptoms

Keywords

Patient

Outcome Measures

Primary Outcomes (1)

• significant difference of REM sleep quantity in polysomnography at day 3

  Day 3

Study Arms (1)

Polysomnography

OTHER

Procedure: Polysomnography

Interventions

Polysomnography PROCEDURE

Polysomnography

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients who had a cardiac surgery with extracorporeal circulation.
• Patients who were extubated at Day 0.
• Patients without any operation or anesthetic complication.
• Patients who speak French.
• Patients without TNC at Day 1.
• Patients who had completed the questionnaires before operation.

You may not qualify if:

• Age \< 18 years old.
• Delirium at Day 1.
• Central nervous system pathology or psychiatric pathology known and treated.
• Concomitant use of neuropsychiatric treatment before surgery that interferes with sleep.
• Clinical condition alteration before polysomnography exam.
• Continue sedation required before Day 3 polysomnography exam.
• Agitation or clinical alteration that did not allow Day 3 polysomnography exam.

Sponsors & Collaborators

• Poitiers University Hospital: lead

Central Study Contacts

Solène QUENTIN-PALOS, PH

CONTACT

0549443159

Study Design

• Study Type: interventional
• Phase: not applicable
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 16, 2015
• First Posted: June 15, 2016
• Primary Completion: March 1, 2018
• Last Updated: October 12, 2016

Record last verified: 2016-10