NCT02800122

Brief Summary

This is an observational retrospective single-center study (CHRU of Nancy) in patients cared for acute dyspnea by a medical team of the emergencies of the CHRU of Nancy. The main purpose of the study is to evaluate the outcome of patients cared for acute dyspnea by a medical team of emergencies of CHRU of Nancy.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
24,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2016

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2016

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

June 6, 2016

Completed
9 days until next milestone

First Posted

Study publicly available on registry

June 15, 2016

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2018

Completed
6.9 years until next milestone

Study Completion

Last participant's last visit for all outcomes

October 25, 2025

Completed
Last Updated

April 18, 2023

Status Verified

April 1, 2023

Enrollment Period

2.8 years

First QC Date

June 6, 2016

Last Update Submit

April 14, 2023

Conditions

Dyspnea; CardiacAcute Disease

Keywords

acute dyspneaemergencyacute heart failure

Outcome Measures

Primary Outcomes (1)

  • All cause in-hospital mortality

    in the last 5 years

Secondary Outcomes (9)

  • Demographic and clinical data of patients cared by a medical team of emergencies

    in the last 5 years

  • Duration of total hospitalization (including emergency stay and conventional hospitalization)

    in the last 5 years

  • The main diagnosis of the initial hospitalization

    in the last 5 years

  • Rate of Brain Natriuretic Peptide (BNP)

    in the last 5 years

  • Administration of non-invasive ventilation and / or diuretics and / or nitrates

    in the last 5 years

  • +4 more secondary outcomes

Study Arms (1)

Patients with acute dyspnea

Patients with acute dyspnea treated by a medical team of emergencies of CHRU of Nancy. All patients admitted to the emergencies in the last 5 years matching the inclusion criteria will be evaluated. About 4,000 patients will be affected, including more than 800 patients with acute heart failure. (Figures based on export of ICD X codes (R06.0: Dyspnea) of patients cared in extra-hospital for acute dyspnea (diagnosis Dyspnea + Heart Failure) over the last 5 years).

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with acute dyspnea cared by a medical team of emergencies of CHRU Nancy in the last 5 years.

You may qualify if:

  • Man or women ≥ 18 years
  • Patients with acute dyspnea cared by a medical team of the emergencies of CHRU of Nancy.

You may not qualify if:

  • Cardiorespiratory arrest before the care by a medical team of the emergencies of the CHRU of Nancy.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHRU Nancy - Service des Urgences

Nancy, 54000, France

RECRUITING

Related Publications (2)

  • Chouihed T, Bassand A, Duarte K, Jaeger D, Roth Y, Giacomin G, Delaruelle A, Duchanois C, Bannay A, Kobayashi M, Rossignol P, Girerd N. Head-to-head comparison of diagnostic scores for acute heart failure in the emergency department: results from the PARADISE cohort. Intern Emerg Med. 2022 Jun;17(4):1155-1163. doi: 10.1007/s11739-021-02879-6. Epub 2021 Nov 17.

    PMID: 34787803DERIVED

  • Chouihed T, Buessler A, Bassand A, Jaeger D, Virion JM, Nace L, Barbe F, Salignac S, Rossignol P, Zannad F, Girerd N. Hyponatraemia, hyperglycaemia and worsening renal function at first blood sample on emergency department admission as predictors of in-hospital death in patients with dyspnoea with suspected acute heart failure: retrospective observational analysis of the PARADISE cohort. BMJ Open. 2018 Mar 30;8(3):e019557. doi: 10.1136/bmjopen-2017-019557.

    PMID: 29602842DERIVED

MeSH Terms

Conditions

DyspneaAcute DiseaseEmergencies

Condition Hierarchy (Ancestors)

Respiration DisordersRespiratory Tract DiseasesSigns and Symptoms, RespiratorySigns and SymptomsPathological Conditions, Signs and SymptomsDisease AttributesPathologic Processes

Study Officials

  • Tahar CHOUIHED, MD, PhD

    Central Hospital, Nancy, France

    PRINCIPAL INVESTIGATOR

  • Nicolas GIRERD, MD

    Central Hospital, Nancy, France

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Tahar CHOUIHED, MD, PhD

CONTACT

+ 33 3 83 15 73 88t.chouihed@chru-nancy.fr

Nicolas GIRERD, MD, PhD

CONTACT

+33383157322n.girerd@chru-nancy.fr

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

June 6, 2016

First Posted

June 15, 2016

Study Start

March 1, 2016

Primary Completion

December 1, 2018

Study Completion

October 25, 2025

Last Updated

April 18, 2023

Record last verified: 2023-04

Data Sharing

IPD Sharing
Will not share

Locations

FR(1)