NCT02799979|Completed
3D Imaging: Prognostic Role in Pulmonary Arterial Hypertension
HTP3S
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HTP3S
Sponsor study identifier
observational
150
1 country
1
Study Start
October 10, 2014
Actual (reported)Primary Completion
October 20, 2021
Actual (reported)Study Completion
February 2, 2022
Actual (reported)Pulmonary hypertension is a rare and severe disease, affecting a young population. Survival is very poor and has been closely related to right ventricular dysfunction. Current prognostic equations rely mostly on right heart catheterization data. The identification of simple echocardiographic prognostic factor is urgently needed. It could help identifying with a non invasive method, high risk patients who could benefit from an intensive specific therapy. 3D right ventricular imaging is a new echocardiographic tool which provides RV volumic analysis, RV ejection fraction, overcoming the classical limits of 2D ultrasound. The aim of this study is to validate a new software for 3D analysis of the right ventricle and assess its prognostic role in pulmonary hypertension. To do so, the investigators will realize a prospective monocentric longitudinal cohort study, including 100 pulmonary hypertension patients. Echocardiographic data will be collected at baseline and after 6 months.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
February 2, 2022
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
October 10, 2014
Actual (reported)May 30, 2016
Actual (reported)June 15, 2016
Actual (reported)October 20, 2021
Actual (reported)February 2, 2022
Actual (reported)Number of death from any cause
Description of the number of death during the study
Baseline to 24 months
Number of Hospitalisation
Baseline to 24 months
3D right ventricular imaging echocardiographic
Baseline and 6 months
Echocardiographic data : 3D right ventricular imaging on 100 pulmonary hypertension patients at Baseline and after six months
Echocardiographic data : 3D right ventricular Imaging on 50 patients without pulmonary hypertension only at baseline
Echocardiographic data (3D right ventricular imaging echocardiographic) will be collected at baseline and after 6months.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Patients with pulmonary hypertension diagnosed
Hopital Pasteur - Chu Nice
Nice, 06000, France
Moceri P, Duchateau N, Baudouy D, Squara F, Bun SS, Ferrari E, Sermesant M. Additional prognostic value of echocardiographic follow-up in pulmonary hypertension-role of 3D right ventricular area strain. Eur Heart J Cardiovasc Imaging. 2022 Oct 20;23(11):1562-1572. doi: 10.1093/ehjci/jeab240.
PAMELA MOCERI, MD
Centre Hospitalier Universitaire de Nice
150 participants (actual enrollment reported by the registry).
First Submitted
May 30, 2016
First Posted
June 15, 2016
Study Start
October 10, 2014
Actual (reported)Contact the study team to confirm eligibility.
Primary Completion
October 20, 2021
Actual (reported)Study Completion
February 2, 2022
Actual (reported)Last Updated
June 16, 2026
Record last verified: 2026-06
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Source: ClinicalTrials.gov.
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