NCT02798640

Brief Summary

The study will evaluate changes in transcutaneous oxygen tension (tcPO2,), and the inferred change in local cutaneous blood flow, in healthy subjects wearing a control and a 100% Celliant® fiber upper torso garment.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
153

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2013

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2013

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2014

Completed
2.4 years until next milestone

First Submitted

Initial submission to the registry

June 9, 2016

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 14, 2016

Completed
Last Updated

June 14, 2016

Status Verified

June 1, 2016

Enrollment Period

4 months

First QC Date

June 9, 2016

Last Update Submit

June 13, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Changes in transcutaneous oxygen tension (tcPO2)

    comparison of individual measurements taken at these time points

    0,30,60,90 minutes

Secondary Outcomes (1)

  • Changes in local skin temperature by infrared imaging

    0,30,60,90 minutes

Study Arms (2)

Active

ACTIVE COMPARATOR

Subject wearing Celliant garment

Device: Celliant

Control

PLACEBO COMPARATOR

Subject wearing non-celliant control garment

Device: Control

Interventions

CelliantDEVICE

100% Celliant garment

Active
ControlDEVICE

Control Garment

Control

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Subjects greater than or equal to18 years of age
  • Men and women between the ages of 18 and 60 years
  • Able to understand and consent to the study
  • Able to follow directions of the Study Coordinators and/or the Principal Investigator
  • Able to complete the study
  • Male or female subjects of any ethnic origin such that the balance across ages and among population groups is reflective of the site population

You may not qualify if:

  • Active smokers
  • No history of cardiovascular disease
  • No history of peripheral vascular disease
  • Engaged in recreational drug use for the six months prior to the start of the study
  • Eaten within two (2) hours of the study
  • Consumed caffeine within four (4) hours prior to the study
  • Consumed alcohol with forty-eight (48) hours prior to the study
  • Subjects with any unstable medical or psychiatric problem
  • Subjects who are pregnant or nursing mothers
  • Subjects who are currently taking part in another clinical study or have taken part in a drug or device study, in the past month.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hologenix, LLC

Santa Monica, California, 90403, United States

Location

Study Officials

  • Ian L Gordon, M.D.

    University of California Medical Center Wound Clinic

    PRINCIPAL INVESTIGATOR
  • Kristopher Washington, B.S.

    Hologenix, LLC

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Study Coordinator

Study Record Dates

First Submitted

June 9, 2016

First Posted

June 14, 2016

Study Start

September 1, 2013

Primary Completion

January 1, 2014

Study Completion

January 1, 2014

Last Updated

June 14, 2016

Record last verified: 2016-06

Data Sharing

IPD Sharing
Will not share

Available IPD Datasets

Informed Consent Form Access
Clinical Investigation plan Access
Clinical Study Report Access

Locations