NCT02797561

Brief Summary

The purpose of this study is to evaluate the effect of FFR (Fractional flow reserve) guided Percutaneous Coronary Intervention in coronary tandem lesions.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
438

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 2016

Longer than P75 for all trials

Geographic Reach
1 country

12 active sites

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 8, 2016

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 13, 2016

Completed
1 month until next milestone

Study Start

First participant enrolled

July 25, 2016

Completed
9.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 13, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 13, 2026

Completed
Last Updated

April 15, 2026

Status Verified

April 1, 2026

Enrollment Period

9.7 years

First QC Date

June 8, 2016

Last Update Submit

April 13, 2026

Conditions

Keywords

Fractional flow reserveTandemPercutaneous Coronary Intervention

Outcome Measures

Primary Outcomes (1)

  • Target vessel failure

    defined as composite event of cardiac death, non-fatal myocardial infarction, target vessel revascularization

    2 years

Secondary Outcomes (15)

  • all cause death

    5 years

  • cardiac death

    5 years

  • myocardial infarction

    5 years

  • target vessel revascularization

    5 years

  • target lesion revascularization

    5 years

  • +10 more secondary outcomes

Study Arms (1)

Tandem lesion evaluated by FFR

Other: 5 year Follow-up

Interventions

Tandem lesion evaluated by FFR

Eligibility Criteria

Age19 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients with tandem lesion evaluated by FFR

You may qualify if:

  • Tandem lesion evaluated by FFR
  • Written consent

You may not qualify if:

  • TIMI flow \< 3
  • Grafted vessel
  • Left ventricular ejection fraction \< 30%
  • Severe calcification and/or severe tortuosity
  • Uncontrolled coronary spasm
  • Life expectancy \< 2 years
  • Planned high risk surgery
  • Pregnancy or breast-feeding

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (12)

Asan Medical Center

Seoul, Songpa-gu, 138-736, South Korea

Location

Soon Chun Hyang University Hospital Bucheon

Bucheon-si, South Korea

Location

Gangwon National Univ. Hospital

Chuncheon, South Korea

Location

Daegu Catholic University Medical Center

Daegu, South Korea

Location

Keimyung University Dongsan Medical Center

Daegu, South Korea

Location

Chungnam National University Hospital

Daejeon, South Korea

Location

Inje University Ilsan Paik Hospital

Ilsan, South Korea

Location

Bundang CHA Hospital

Seongnam, South Korea

Location

Seoul National University Bundang hospital

Seongnam, South Korea

Location

Seoul National University hospital

Seoul, South Korea

Location

Wonju Severance Christian Hospital

Wŏnju, South Korea

Location

Pusan National University Yangsan Hospital

Yangsan, South Korea

Location

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
professor of medicine

Study Record Dates

First Submitted

June 8, 2016

First Posted

June 13, 2016

Study Start

July 25, 2016

Primary Completion

April 13, 2026

Study Completion

April 13, 2026

Last Updated

April 15, 2026

Record last verified: 2026-04

Locations