NCT02793102

Brief Summary

In the literature the use of olfactory dimension in the treatment of anorexia has not been verified experimentally. The investigator hypothesize that the therapeutic use of a dietary nature olfactory stimuli in anorexia nervosa promotes food recovery. The team propose a prospective study over a period of 12 months in which we use the Body Mass Index (BMI) as the primary endpoint of the state of anorexia nervosa patients.

Trial Health

15
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Sep 2012

Typical duration for not_applicable

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2012

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2015

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

June 3, 2016

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 8, 2016

Completed
Last Updated

June 8, 2016

Status Verified

June 1, 2016

Enrollment Period

2.5 years

First QC Date

June 3, 2016

Last Update Submit

June 3, 2016

Conditions

Keywords

mental anorexiasensory workshopsBMI

Outcome Measures

Primary Outcomes (1)

  • Assess the impact of sensory workshops on BMI Body Mass Indexat 6 months and 12 months

    The primary endpoint is the M6 and increase maintenance M12 BMI Body Mass Index to \<or = 2.6kg / m2

    Comparaison to baseline and 6 month after and maintenance at month 12

Study Arms (2)

Olfactory workshop + Somesthesia workshop

EXPERIMENTAL

Olfactory workshop, Twenty odorants. Somesthesia workshop, time for moving the body, Talk Time

Other: Olfactory workshopOther: Somesthesia workshop

Auditory workshop + Somesthesia workshop

EXPERIMENTAL

Auditory workshop, Twenty extracts of music tracks. Somesthesia workshop, time for moving the body, Talk Time

Other: Somesthesia workshopOther: Auditory workshop

Interventions

Twenty odorants are selected: 10 evoke a food (including 5 pleasant and unpleasant 5) and 10 suggest a non-food source

Olfactory workshop + Somesthesia workshop

Kinesthetic time or time for moving the body (30 min), and kinesthetic sensations (duration 10 min), and Talk Time

Auditory workshop + Somesthesia workshopOlfactory workshop + Somesthesia workshop

Twenty extracts of music tracks (30 seconds each) are built in the same fashion as those used during the workshops, but are different.

Auditory workshop + Somesthesia workshop

Eligibility Criteria

Age11 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Diagnosis of anorexia nervosa according to DMS IV-TR (Diagnostic and Statistical Manual of Mental Disorders) criteria.
  • Follow Outpatient care or hospitalization
  • Able to respond to the clinical evaluation questionnaires
  • Affiliated to the social security system
  • Consentement Informed of the legal representative and the patient

You may not qualify if:

  • Somatic comorbidity associated diabetes, celiac disease, brain tumor.
  • Intolerance Odors, predisposition to develop asthma and / or respiratory allergies.
  • Pathologie Chronic of nose and sinus.
  • Hyposmic Or anosmic.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Anorexia

Condition Hierarchy (Ancestors)

Signs and Symptoms, DigestiveSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Florence ASKENAZY, MD

    Fondation Lenval

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 3, 2016

First Posted

June 8, 2016

Study Start

September 1, 2012

Primary Completion

March 1, 2015

Study Completion

March 1, 2015

Last Updated

June 8, 2016

Record last verified: 2016-06

Data Sharing

IPD Sharing
Will not share