NCT02791295

Brief Summary

The purpose of the study is to determine whether a personalized lifestyle intervention focused on diet and physical activity reinforcement is effective in avoiding weight gain in the first months following initiation of subcutaneous insulin pump therapy in type-2 diabetic patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
54

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Oct 2016

Longer than P75 for not_applicable

Geographic Reach
1 country

6 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 1, 2016

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 6, 2016

Completed
4 months until next milestone

Study Start

First participant enrolled

October 4, 2016

Completed
4.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 19, 2021

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 17, 2021

Completed
Last Updated

March 19, 2021

Status Verified

March 1, 2021

Enrollment Period

4.3 years

First QC Date

June 1, 2016

Last Update Submit

March 17, 2021

Conditions

Keywords

Type 2 diabeteslifestyle interventioninsulin pump treatmentbody weightbody composition

Outcome Measures

Primary Outcomes (1)

  • Weight change

    The difference in body weight changes between the two groups over a six-month period following initiation of insulin pump treatment.

    6 months

Secondary Outcomes (5)

  • Glycemic control

    6 months

  • Body composition

    6 months

  • Diabetes Treatment Satisfaction

    6 months

  • Intermediate weight change

    3 months

  • Retention of weight change

    1 year

Study Arms (2)

Diet and physical activity program

EXPERIMENTAL

Diet and physical activity program with individual coaching

Other: Diet and physical activity program

control

NO INTERVENTION

standard care

Interventions

A personalized intervention focused on improving diet and increasing physical activity will be implemented at-home with a monthly support by a registered dietician and physical activity educator during 6 months

Diet and physical activity program

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult Type 2 diabetic patients with indication of initiation of insulin pump therapy.
  • Patients addressed for the insulin pump follow-up to the home care provider supporting the study.
  • Public health care security affiliation.

You may not qualify if:

  • Breastfeeding or pregnant woman.
  • Not willing to participate as assessed by the investigator.
  • Patients unable to ride a training bike.
  • Unavailable in the next 6 months.
  • Patient without a medical certificate done in the last 12 months by a cardiologist attesting the ability to participate in a physical activity reinforcement program.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

Annecy-Genevois Hospital

Annecy, 74370, France

Location

Pierre Oudot Hospital

Bourgoin, 38302, France

Location

Métropole Savoie Hospital

Chambéry, 73000, France

Location

Alpes Léman Hospital

Contamine-sur-Arve, 74130, France

Location

Grenoble University Hospital

Grenoble, 38043, France

Location

Marseille European Hospital

Marseille, 13003, France

Location

MeSH Terms

Conditions

Diabetes Mellitus, Type 2Body Weight

Interventions

Diet

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Nutritional Physiological PhenomenaDiet, Food, and NutritionPhysiological Phenomena

Study Officials

  • Anne-Laure Borel, MD PhD

    University Hospital, Grenoble

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 1, 2016

First Posted

June 6, 2016

Study Start

October 4, 2016

Primary Completion

January 19, 2021

Study Completion

March 17, 2021

Last Updated

March 19, 2021

Record last verified: 2021-03

Data Sharing

IPD Sharing
Will not share

Locations