Mirror Box Imaging Study
Effects of Mirror Box Therapy on Neuroplasticity and Functional Outcome in Hemiparetic Upper Limb Post Stroke
1 other identifier
interventional
40
1 country
1
Brief Summary
The purpose of this study is to evaluate the effects of mirror box therapy on upper extremity, motor recovery and motor functioning in patients that have suffered a stroke.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable stroke
Started Apr 2016
Longer than P75 for not_applicable stroke
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 2016
CompletedFirst Submitted
Initial submission to the registry
April 7, 2016
CompletedFirst Posted
Study publicly available on registry
May 18, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2022
CompletedJune 1, 2022
May 1, 2022
6 years
April 7, 2016
May 30, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
Change in brain connectivity will be assessed by resting-state fMRI
Baseline, 3 weeks and at 6 weeks
Secondary Outcomes (4)
Activity of daily living will be assessed with Barthel index.
Baseline, 3 weeks and at 6 weeks
Function of the affected hemiplegic upper limb will be assessed with action research arm test
Baseline, 3 weeks and at 6 weeks
Impairment in the hemiplegic upper limb will be assessed with Fugl Meyer test.
Baseline, 3 weeks and at 6 weeks
Grip strength will be assessed using hand dynamometer
Baseline, 3 weeks and at 6 weeks
Study Arms (2)
Mirror box therapy
EXPERIMENTALThe participants in the mirror box therapy arm will receive mirror box therapy for 3 weeks for upper limb rehabilitation post stroke.
Standard treatment group
NO INTERVENTIONThe participants will receive the standard treatment arm for 3 weeks for upper limb rehabilitation post stroke.
Interventions
In mirror box therapy the patient uses the reflection of their good arm to trick to brain into thinking that the effected arm is working.
Eligibility Criteria
You may qualify if:
- yrs to 105yrs
- Hemiparetic upper limb post stroke
- Capable of providing informed consent
- Intact vision: if diagnosis of peripheral field defect, patient should be able to compensate for it.
You may not qualify if:
- Any contraindication to MRI scanning
- Clinically significant psychiatric disorder (e.g. depression)
- Pre-existing neurological or psychiatric disease that could confound the study results.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Mid and South Essex NHS Foundation Trustlead
- Anglia Ruskin Universitycollaborator
Study Sites (1)
Southend Hospital
Westcliff-on-Sea, Essex, SS0 0RY, United Kingdom
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Iris Grunwald
Anglia Ruskin University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- TREATMENT
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 7, 2016
First Posted
May 18, 2016
Study Start
April 1, 2016
Primary Completion
April 1, 2022
Study Completion
April 1, 2022
Last Updated
June 1, 2022
Record last verified: 2022-05
Data Sharing
- IPD Sharing
- Will not share