NCT02768896

Brief Summary

Voltage fluctuation as a result of brain activity will be recorded into the computer using an EEG device.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2016

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 4, 2016

Completed
1 month until next milestone

First Posted

Study publicly available on registry

May 11, 2016

Completed
21 days until next milestone

Study Start

First participant enrolled

June 1, 2016

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2018

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2018

Completed
Last Updated

June 7, 2016

Status Verified

June 1, 2016

Enrollment Period

1.6 years

First QC Date

April 4, 2016

Last Update Submit

June 6, 2016

Conditions

Outcome Measures

Primary Outcomes (3)

  • Voltage fluctuation resulting from brain activity after visual stimuli

    Change in brain wave activity after visual stimuli as compared with baseline measured in tens of micro-volts per second.

    One hour

  • Voltage fluctuation resulting from brain activity after auditory stimuli

    Change in brain wave activity after auditory stimuli as compared with baseline measured in tens of micro-volts per second.

    One hour

  • Voltage fluctuation resulting from brain activity after visual and auditory stimuli

    Change in brain wave activity after visual and auditory stimuli as compared with baseline measured in tens of micro-volts per second.

    One hour

Study Arms (4)

Baseline

NO INTERVENTION

Patients will walk naturally with EEG measuring brain waves

Visual stimuli

EXPERIMENTAL

Patients will walk naturally with EEG measuring brain waves while seeing a grid through glasses

Behavioral: BaselineBehavioral: visual stimuli

Auditory stimuli

EXPERIMENTAL

Patients will walk naturally with EEG measuring brain waves while hearing an auditory stimuli

Behavioral: BaselineBehavioral: Auditory stimuli

Visual and auditory stimuli

EXPERIMENTAL

Patients will walk naturally with EEG measuring brain waves while seeing a grid through glasses and hearing an auditory stimuli simultaneously

Behavioral: BaselineBehavioral: Visual and auditory stimuli

Interventions

BaselineBEHAVIORAL

Patients will walk naturally with EEG measuring brain waves

Auditory stimuliVisual and auditory stimuliVisual stimuli
visual stimuliBEHAVIORAL

Patients will walk naturally with EEG measuring brain waves while seeing a grid through glasses

Visual stimuli

Patients will walk naturally with EEG measuring brain waves while hearing an auditory stimuli

Auditory stimuli

Patients will walk naturally with EEG measuring brain waves while seeing a grid through glasses and hearing an auditory stimuli simultaneously

Visual and auditory stimuli

Eligibility Criteria

Age18 Years - 99 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with Parkinson's disease that are ambulatory and can sign a written informed consent

You may not qualify if:

  • Patients with Parkinson's disease who are not ambulatory
  • Patients with dementia
  • Patients that are blind
  • Patients that have severe hearing impairment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Parkinson Disease

Interventions

BaseLine dental cement

Condition Hierarchy (Ancestors)

Parkinsonian DisordersBasal Ganglia DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesMovement DisordersSynucleinopathiesNeurodegenerative Diseases

Study Officials

  • Ilana Schlesinger, MD

    Rambam Health Care Campus

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Ilana Schlesinger, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 4, 2016

First Posted

May 11, 2016

Study Start

June 1, 2016

Primary Completion

January 1, 2018

Study Completion

February 1, 2018

Last Updated

June 7, 2016

Record last verified: 2016-06

Data Sharing

IPD Sharing
Will not share