Appetite and Adiposity Across a Continuum of Activity

NCT02763449 | Unknown

• 1 other identifier: AAA-1
• Study Type: interventional
• Target: 40
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purpose of this study is to understand what happens when someone either becomes more active or more inactive. This study will measure your energy intake, energy expenditure, and body composition under normal conditions, when you become active, and when you become inactive.

Conditions

Physical Activity and Sedentary Behavior

Outcome Measures

Primary Outcomes (1)

• Appetite- subjective

  Change in appetite will be assessed through subjective ratings of hunger and fullness

  14 days

Secondary Outcomes (1)

• Appetite- objective

  14 days

Study Arms (2)

Sedentary

EXPERIMENTAL

Individuals will reduce their physical activity level for 14-days

Behavioral: Self-monitoing

Active

EXPERIMENTAL

Individuals will increase their physical activity level for 14-days

Behavioral: Self-monitoing

Interventions

Self-monitoing BEHAVIORAL

Participants will self-monitor their physical activity level via activity monitors

Active; Sedentary

Eligibility Criteria

• Age: 25 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Men and women
• Age 25-35 yrs
• BMI ≥25.0 to \<35.0 kg/m2
• Subjective physical activity (pre run-in): Sedentary for the previous 3 months (\< 20min, 3 times/week of structured exercise)
• Objective physical activity (run-in): daily steps/day \>4500 yet \<7,000 during 7 day run-in period
• Weight-stable (± 5%) within the previous 3 months
• Non-smoking for last year
• Able to provide own transportation to study visits and intervention
• Not currently involved in any other research study
• Willing and able to participate in all aspects of the trial including research testing
• Willing to give informed consent to participate
• Able to participate in a moderate physical exercise program

You may not qualify if:

• Self-reported significant cardiovascular disease including but not limited to serious arrhythmias, cardiomyopathy, congestive heart failure, myocardial infarction, stroke
• Other self-reported medical conditions including but not limited to metabolic disorders such as diabetes, chronic or recurrent respiratory conditions, active cancer, musculoskeletal disease interfering with exercise, or any serious medical condition that may affect adherence to the protocol or exercising safely, or be aggravated by exercise
• Medications known to affect exercise performance or metabolism (e.g. thyroid medication, beta-blockers, or stimulants)
• Excess caffeine use (\> 500mg/day)
• Restrained eater (\>13) on the restraint section of the three-factor eating questionnaire
• Current or past diagnosis of an eating disorder
• Any self-reported contraindications to exercise according to the American College of Sports Medicine criteria
• Pregnant or actively trying to become pregnant
• Gave birth in the past 12 months or \<6 months post-lactation
• Other medical, psychiatric or behavioral factors that in the judgment of the principal investigator may interfere with study participation or the ability to follow the intervention protocol.
• Known allergy to the metal nickel
• Known allergies to pasta or tomato sauce

Sponsors & Collaborators

• Iowa State University: lead

MeSH Terms

Conditions

Motor Activity; Sedentary Behavior

Condition Hierarchy (Ancestors)

Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: April 4, 2016
• First Posted: May 5, 2016
• Study Start: May 1, 2016
• Primary Completion: October 1, 2017
• Study Completion: December 1, 2018
• Last Updated: May 5, 2016

Record last verified: 2016-05