NCT02761538

Brief Summary

The investigators developed the Aviitam® online platform. The purpose of the project is to test the medico-economic impact related to the utilization of the Aviitam online platform in primary care. Primary objective: To assess the cost-effectiveness at 24 months follow-up of the utilization of the Aviitam® online software in primary care for people with obesity and at least one comorbidity compared to a usual follow-up in primary care. Secondary objectives: Weight loss; quality of life ; blood pressure change; changes in lipid profile, blood glucose and HbA1c; physician satisfaction; patients satisfaction, profiling of patients and data mining analysis on the collected data. Method : Overweight \& obese patients with associated comorbidities will receive a 24 months follow-up to assess the impact of the use of the online platform Aviitam®. Practitioners will be randomized by lot between an Aviitam® group and a control group (usual care). A medico-economic analysis will be conducted with a cost-effectiveness analysis and a budget impact analysis. With no hypothesis on the primary endpoint, the calculation of the required number of subjects was based on the quality of life. 150 patients will be included per group Patients of the 2 groups will be assessed at baseline and after 24 months. The first day of each month, each patient included in the study will receive a questionnaire to fill online to evaluate their health care consumption in the previous month and the EQ5D questionnaire , a standardized questionnaire validated in French to assess the effects on health and to be used to calculate cost - utility. Expected results and perspectives Proving the effectiveness of the Aviitam® online program focused on non-drug therapies and therapeutic lifestyle changes for overweight and obesity management with reduced health costs, improvement in quality of life, reduction in weight and improvement of comorbidities. In terms of public health, the use of the platform Aviitam® can be expect to improve management of excess body weight and reduced health costs. Furthermore, Aviitam® could be a valuable tool to support healthcare professionals in outpatient therapeutic education approaches.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
300

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2015

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 17, 2015

Completed
19 days until next milestone

First Submitted

Initial submission to the registry

October 6, 2015

Completed
7 months until next milestone

First Posted

Study publicly available on registry

May 4, 2016

Completed
3.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2019

Completed
Last Updated

February 8, 2019

Status Verified

February 1, 2019

Enrollment Period

4.2 years

First QC Date

October 6, 2015

Last Update Submit

February 7, 2019

Conditions

Keywords

obesityOverweightICTsCost-effectiveness

Outcome Measures

Primary Outcomes (2)

  • Weight loss

    Weight loss expressed in kg

    24 months follow-up

  • "Quality of life" (scale)

    Variation of scale in quality of life "Quality of life assessed by Health-Related Quality of Life (HRQOL) between M0 and M24

    24 months follow-up

Secondary Outcomes (7)

  • Systolic blood pressure (mmHg)

    24 months

  • Diastolic blood pressure (mmHg)

    24 months

  • Blood LDL Cholesterol (mmol/l)

    24 months

  • Blood HDL Cholesterol (mmol/l)

    24 months

  • Blood Triglycerides (mmol/l)

    24 months

  • +2 more secondary outcomes

Study Arms (2)

AVIITAM Group

EXPERIMENTAL

Utilization of the web platform Aviitam

Behavioral: AVIITAM

Control group

NO INTERVENTION

No utilization of web-platform Aviitam

Interventions

AVIITAMBEHAVIORAL

The purpose of the project is to test the medico economic impact related to the utilization of the Aviitam online platform in primary care. . .

AVIITAM Group

Eligibility Criteria

Age35 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • With a BMI between 25 and 45 kg / m2 and at least one of the following criteria associated:
  • A known hypertension treated or not
  • A known prediabetes \[fasting glucose between 110 and 126 mg / l or metabolic syndrome as defined in the 2009 consensus of the International Diabetes Federation and the American heart Association.
  • A known type 2 diabetes, treated or not
  • A known dyslipidemia treated or not
  • A known sleep disorder
  • A known history of cardiovascular disease\> 6 months, a stable known cardiovascular disease, peripheral arterial disease.

You may not qualify if:

  • No Having signed an informed written consent
  • No Being affiliated to social security

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Departement Nutrition Diabète Hôpital lapeyronie 371 avenue du Doyen Gaston Giraud

Montpellier, 34295, France

RECRUITING

Montpellier University Hospital

Montpellier, 34295, France

RECRUITING

MeSH Terms

Conditions

ObesityOverweight

Condition Hierarchy (Ancestors)

OvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Antoine AA Avignon, PUPH

    University Hospital, Montpellier

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Antoine AA AVIGNON, PU-PH

CONTACT

Antoine AA Avignon, PU PH

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 6, 2015

First Posted

May 4, 2016

Study Start

September 17, 2015

Primary Completion

December 1, 2019

Study Completion

December 1, 2019

Last Updated

February 8, 2019

Record last verified: 2019-02

Data Sharing

IPD Sharing
Will not share

Locations