NCT02755974|Recruiting
The London COPD Exacerbation Cohort
EXCEL_Cohort
Relationship Between Patient Phenotypes and Exacerbations in Chronic Obstructive Pulmonary Disease.
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EXCEL_Cohort
Relationship Between Patient Phenotypes and Exacerbations in Chronic Obstructive Pulmonary Disease.
Sponsor study identifier
observational
300
1 country
1
Study Start
January 2009
Actual (reported)Primary Completion
December 31, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
December 31, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
The London COPD exacerbation (EXCEL) cohort builds on an established cohort started in 1995 and designed to study COPD exacerbations and their impact on health-status and disease progression.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 31, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 2009
Actual (reported)April 13, 2016
Actual (reported)April 29, 2016
Actual (reported)December 31, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
December 31, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Annual exacerbation rate (number of exacerbations over a 12 month period)
Definition of an exacerbation * The presence of 2 new symptoms (one of which must be major) for 2 consecutive days * Major symptoms: increased breathlessness (A), increased sputum colour (B1) or increased sputum amount (B2) * Minor symptoms: a cold (C), increased wheeze or chest tightness (D), Sore throat (E1), Increased cough (E2), Fever (F)
12 months
Patients with COPD who are generally seen in outpatient clinic.
National Heart and Lung Institute, Imperial College
London, SW3 6LR, United Kingdom
Blood, Sputum, Urine, Bronchoscopy brushing and Lavage fluid, DNA
Jadwiga Wedzicha
Imperial College London
First Submitted
April 13, 2016
First Posted
April 29, 2016
Study Start
January 2009
Actual (reported)Primary Completion
December 31, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Enhancement of in-Vitro GC Function in Patients With COPD
Contact the study team to confirm eligibility.
Study Completion
December 31, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
June 21, 2022
Record last verified: 2022-06
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Source: ClinicalTrials.gov.
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