Potlako: A Programmatic Intervention to Improve Access to Timely Oncology Care

NCT02752061 | Completed

• 1 other identifier: BHP078
• Study Type: interventional
• Target: 979
• Locations: 1 country
• Sites: 1

Brief Summary

Diagnostic and treatment delays contribute substantially to disparities in cancer morbidity and mortality between low- and middle- income countries (LMICs) and high-income countries. Individuals present with advanced stage disease resulting in minimal chance for cure or long-term survival. The Potlako project will implement and evaluate a multifaceted intervention to test the hypothesis that a package of enhanced coordination of care including an electronic messaging, transportation support, and training targeted at generalist clinicians at primary and secondary level facilities, can reduce time to diagnosis and stage at diagnosis for HIV-infected individuals with cancer.

Conditions

Neoplasms; HIV; Healthcare Disparity

Outcome Measures

Primary Outcomes (2)

• Cancer stage

  1 day visit

• Time from initial clinic visit with cancer symptom/sign to entry into oncology care

  1 day visit

Study Arms (2)

Kweneng East District

EXPERIMENTAL

Patient presenting with possible cancer symptoms/sign to a clinic or hospital in Kweneng East District during study period.

Other: Potlako intervention

All other districts

NO INTERVENTION

Patient presenting with possible cancer symptoms/sign to a clinic or hospital in all other districts of Botswana (or Kweneng East prior to implementation of intervention).

Interventions

Potlako intervention OTHER

Multicomponent intervention including: * provider training on early detection and diagnostic approaches to cancer * patient education on importance of obtaining timely cancer diagnosis * provision of a patient navigator to facilitate diagnosis and entry into care * provision of transportation support to vulnerable patients

Kweneng East District

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Citizen of Botswana
• Suspected or diagnosed cancer

You may not qualify if:

• Involuntary incarceration

Sponsors & Collaborators

• Harvard School of Public Health (HSPH): lead
• Brigham and Women's Hospital: collaborator
• Botswana Harvard AIDS Institute Partnership: collaborator
• Botswana Ministry of Health: collaborator
• Dana-Farber Cancer Institute: collaborator

Study Sites (1)

Botswana Harvard AIDS Institute

Gaborone, Botswana

Location

Related Publications (1)

• Tapela NM, Peluso MJ, Kohler RE, Setlhako II, Botebele K, Gabegwe K, Nkele I, Narasimhamurthy M, Mmalane M, Grover S, Barak T, Shulman LN, Lockman S, Dryden-Peterson S. A Step Toward Timely Referral and Early Diagnosis of Cancer: Implementation and Impact on Knowledge of a Primary Care-Based Training Program in Botswana. Front Oncol. 2018 May 29;8:187. doi: 10.3389/fonc.2018.00187. eCollection 2018.

  PMID: 29896450 DERIVED

MeSH Terms

Conditions

Neoplasms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor, Research Affiliate

Study Record Dates

• First Submitted: April 22, 2016
• First Posted: April 26, 2016
• Study Start: May 13, 2016
• Primary Completion: July 21, 2020
• Study Completion: July 21, 2020
• Last Updated: July 23, 2020

Record last verified: 2020-07

Locations

BO (1)