Study of the Personal Identity in Adults With Autism Spectrum Disorder Without Intellectual Deficiency

NCT02747056 | Completed

• 1 other identifier: 6282
• Study Type: interventional
• Target: 102
• Locations: 1 country
• Sites: 1

Brief Summary

The research aims at clarifying the impact of autism on personal identity in adulthood. Two studies will be made in order to compare adults with autistic spectrum disorders without intellectual deficiency and controls. In the first study (Study A), the investigators will ask subjects to tell autobiographical memories and to specify their characteristics by answering focused questions. In the second study (Study B), the investigators will ask subjects to say the self statements which define them. Then, subjects will have to tell and to specify the characteristics of the autobiographical memories linked to these self statements.

Conditions

Autism Spectrum Disorders

Outcome Measures

Primary Outcomes (1)

• The number of details in the memory (A)/The specificity of the memory (B)

  study A:The number of details is the total number of perceptual/sensory, temporal, contextual, emotional and cognitive details found in the memory after spontaneous recall first. Secondly, the investigators will ask subjects to clarify the five characteristics of the details presented upper and retrieval should be make easier with specific cueing. Study B:The specificity measures how the memory is focused on specific date, space, context, emotions, thoughts and feelings. The specificity of the memories is deeply linked to the self .

  The number of details or the specificity of the memory is assessed from 1 day to 3 months after the inclusion/baseline

Secondary Outcomes (14)

• Study A and B: Autistic symptoms questionnaire 1

  the Autistic symptoms will be assessed during the initiation/baseline visit at V1

• Study A and B: Autistic symptoms questionnaire 2

  the Autistic symptoms will be assessed during the initiation/baseline visit at V1

• Study A and B: Autistic symptoms questionnaire 3

  the Autistic symptoms will be assessed during the initiation/baseline visit at V1

• Study A and B:Executives functions, test 1

  Executives functions will be assessed during the initiation/baseline visit (V1)

• Study Aand B:Executives functions test 2

  Executives functions will be assessed during the initiation/baseline visit (V1)

Study Arms (8)

Autism spectrum disorder studyA part1

EXPERIMENTAL

The subjects will perform clinical, psychological and neuropsychological assessment. the subjects will do 3 tests about executive functions. Finally, the participants will complete 3 questionnaires about autism and 3 questionnaires about the self concept.

Autism spectrum disorder studyA part2

EXPERIMENTAL

The subjects will perform Autobiographical memories Assessment. The subjects will tell autobiographical memories freely first and secondly by answering focused questions to specify the characteristics of subjects' memories

Other: Autobiographical memories Assessment

Control adults Study A, part 1

OTHER

The subjects will perform clinical, psychological and neuropsychological assessment. The subjects will do 3 tests about executive functions. The participants will complete 3 questionnaires about autism and 3 questionnaires about the self concept.

Other: clinical, psychological and neuropsychological assessment

Control adults Study A, part 2

OTHER

The subjects will perform Autobiographical memories Assessment. The subjects will tell autobiographical memories freely first and secondly by answering focused questions to specify the characteristics of subjects' memories

Other: Autobiographical memories Assessment

Autism spectrum disorder Study B, part 1

EXPERIMENTAL

The subjects will perform clinical, psychological and neuropsychological assessment. The subjects will do 3 tests about executive functions. The participants will complete 3 questionnaires about autism and 3 questionnaires about the self concept.

Other: clinical, psychological and neuropsychological assessment

Autism spectrum disorder Study B, part 2

EXPERIMENTAL

The subjects will perform Autobiographical memories assessment characteristics. The subjects will say the self statements which define them. Then, the participants will have to tell and specify the characteristics of the autobiographical memories linked to the self statements.

Other: Autobiographical memories assessment characteristics

Control adults, Study B part 1

OTHER

The subjects will perform clinical, psychological and neuropsychological assessment.The subjects will do 3 tests about executive functions. Finally, the participants will complete 3 questionnaires about autism and 3 questionnaires about the self concept.

Other: clinical, psychological and neuropsychological assessment

Control adults, Study B part 2

OTHER

The subjects will perform Autobiographical memories assessment characteristics. The subjects will say the self statements which define them. Then, the participants will have to tell and specify the characteristics of the autobiographical memories linked to the self statements

Other: Autobiographical memories assessment characteristics

Interventions

clinical, psychological and neuropsychological assessment OTHER

the subjects will do 3 tests about executive functions, complete 3 questionnaires about autism and 3 questionnaires about the self concept

Autism spectrum disorder Study B, part 1; Control adults Study A, part 1; Control adults, Study B part 1

Autobiographical memories Assessment OTHER

The investigators will ask subjects to tell autobiographical memories freely first and, secondly, to specify participants'characteristics by answering focused questions.

Autism spectrum disorder studyA part2; Control adults Study A, part 2

Autobiographical memories assessment characteristics OTHER

During the second time point, the investigators will ask subjects to say the self statements which define them. Then, subjects will have to tell and to specify the characteristics of the autobiographical memories linked to these self statements.

Autism spectrum disorder Study B, part 2; Control adults, Study B part 2

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• adults with autism spectrum disorders
• to 65 years old

You may not qualify if:

• treatment with benzodiazepines
• Study A \& B, control adults
• healthy volunteers
• to 65 years old
• psychiatric disorders

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Hôpitaux universitaires de Strasbourg

Strasbourg, 67091, France

Location

Related Publications (1)

• Coutelle R, Goltzene MA, Bizet E, Schoenberger M, Berna F, Danion JM. Self-concept Clarity and Autobiographical Memory Functions in Adults with Autism Spectrum Disorder Without Intellectual Deficiency. J Autism Dev Disord. 2020 Nov;50(11):3874-3882. doi: 10.1007/s10803-020-04447-x.

  PMID: 32146597 RESULT

MeSH Terms

Conditions

Autism Spectrum Disorder

Interventions

Neuropsychological Tests

Condition Hierarchy (Ancestors)

Child Development Disorders, Pervasive; Neurodevelopmental Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Psychological Tests; Behavioral Disciplines and Activities

Study Officials

• Jean Marie DANION, Prof

  Hôpitaux Universitaires de Strasbourg

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 7, 2016
• First Posted: April 21, 2016
• Study Start: June 1, 2016
• Primary Completion: August 1, 2019
• Study Completion: October 11, 2019
• Last Updated: December 19, 2025

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)