Food and the Brain
Emotion and Reward Processing in Binge Eating
1 other identifier
observational
83
1 country
1
Brief Summary
The proposed study will examine the role of reward and emotion in women with and without a history of binge eating. It is important to understand how the brain responds to reward and emotion in binge eating in order to identify different pathways toward binge eating and provide individualized targets for treatment. This is particularly important in light of the fact that for many patients, the current treatments for binge eating are not effective.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jan 2016
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2016
CompletedFirst Submitted
Initial submission to the registry
April 12, 2016
CompletedFirst Posted
Study publicly available on registry
April 19, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2020
CompletedOctober 20, 2020
October 1, 2020
4.3 years
April 12, 2016
October 19, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
Brain activity during rest
Functional magnetic resonance imaging will be used to measure brain activity at rest and connectivity between brain regions will be examined.
Baseline
Brain activity during emotion conflict
Functional magnetic resonance imaging will be used to measure brain activity during a task where participants respond to images of faces with emotional expressions overlaid with an emotion word written in text. We will focus on brain response during this task when emotion face vs word are in conflict.
Baseline
Brain activity during monetary wins and losses
Functional magnetic resonance imaging will be used to measure brain activity during a game where participants can win or lose money if they respond to a shape on the computer screen. Brain response during wins and losses will be examined.
Baseline
Study Arms (1)
Women ages 18-35
Women ages 18-35 who do and do not engage in binge eating will be included in the study
Eligibility Criteria
Women ages 18-35
You may qualify if:
- Female
- Ages 18-35
- with or without current binge eating behaviors
You may not qualify if:
- Any contraindication for MRI (orthodontia, vascular stents, metallic ear tubes, metal implants, piercings, etc).
- substance abuse
- traumatic brain injury
- BMI \< 18.5
- pregnant women
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Stanford University, Department of Psychiatry
Stanford, California, 94305, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Cara Bohon, PhD
Stanford University
Study Design
- Study Type
- observational
- Observational Model
- ECOLOGIC OR COMMUNITY
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Professor
Study Record Dates
First Submitted
April 12, 2016
First Posted
April 19, 2016
Study Start
January 1, 2016
Primary Completion
April 1, 2020
Study Completion
April 1, 2020
Last Updated
October 20, 2020
Record last verified: 2020-10