NCT02742064

Brief Summary

The purpose of this study is to determine if a mobile sensing platform can passively and objectively detect the presence of clinically significant mood disorder symptomatology and symptom progression over time. Meeting this goal will allow for improved risk categorization, prediction of relapse, and measurement of disease progression in a lifetime prevalence population.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
899

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Feb 2015

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2015

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

April 11, 2016

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 18, 2016

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2017

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2018

Completed
Last Updated

July 17, 2018

Status Verified

July 1, 2018

Enrollment Period

2.9 years

First QC Date

April 11, 2016

Last Update Submit

July 16, 2018

Conditions

Outcome Measures

Primary Outcomes (2)

  • Severity of MDD symptoms as assessed by QIDS SR

    6 months

  • Severity of Mania symptoms as assessed by ASRM

    6 months

Study Arms (3)

MDD-Single Episode

1\. Subjects who have experienced 1 episode of major depressive disorder (MDD) in their lifetime.

Other: Cogito Companion Mobile Phone Application

MDD-Recurrent

1\. Subjects who have experienced 2 or more episodes of depressive disorder (MDD) in their lifetime.

Other: Cogito Companion Mobile Phone Application

Bipolar Disorder

1\. Subjects who have been diagnosed with bipolar disorder in their lifetime.

Other: Cogito Companion Mobile Phone Application

Interventions

Also known as: Cogito Mobile Sensing Platform
Bipolar DisorderMDD-RecurrentMDD-Single Episode

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Participants will be selected from the MoodNetwork, an online network of individuals with mood disorders, which is hosted by MGH. A subset of participants with mood disorders enrolled in MoodNetwork will download Cogito's mobile sensing platform on their mobile phones.

You may qualify if:

  • Age 18 or older
  • Have a smartphone and cell service plan, including voice and data, that meets the device requirements of the Mobile Sensing Platform.
  • Enrolled in the MoodNetwork

You may not qualify if:

  • Report positively on the QIDS-SR suicide item during study intake
  • Total score greater than 15 on the QIDS-SR during the screening process

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Massachusetts General Hospital

Boston, Massachusetts, 02114, United States

Location

MeSH Terms

Conditions

DepressionBipolar Disorder

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehaviorBipolar and Related DisordersMood DisordersMental Disorders

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 11, 2016

First Posted

April 18, 2016

Study Start

February 1, 2015

Primary Completion

December 31, 2017

Study Completion

March 31, 2018

Last Updated

July 17, 2018

Record last verified: 2018-07

Data Sharing

IPD Sharing
Will not share

Locations