NCT02738086

Brief Summary

This pilot study will use mobile-health technology to deliver an intervention designed for lasting physical activity behavior change. The study will assess the feasibility of using the Physical Activity Behavior Change(PABC) intervention for Veterans with lower limb amputation. This intervention will be delivered using wrist-worn wearable activity sensors and a home-based tablet computer to allow real-time physical activity feedback and video interface between the participants and the therapist.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
31

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2016

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 16, 2016

Completed
29 days until next milestone

First Posted

Study publicly available on registry

April 14, 2016

Completed
3 months until next milestone

Study Start

First participant enrolled

July 1, 2016

Completed
2.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 22, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 22, 2019

Completed
12 months until next milestone

Results Posted

Study results publicly available

February 18, 2020

Completed
Last Updated

February 18, 2020

Status Verified

February 1, 2020

Enrollment Period

2.6 years

First QC Date

March 16, 2016

Results QC Date

January 10, 2020

Last Update Submit

February 6, 2020

Conditions

Keywords

AmputationPhysical ActivityRehabilitation

Outcome Measures

Primary Outcomes (4)

  • Retention Rate

    Retention rate will be measured as the percent of participants enrolled in the intervention who complete the intervention.

    3 months

  • Dose Goal Attainment

    Dose goal attainment will be measured as the percent of participants in the intervention phase of the study who meet the dose goal of an average 3% increase in daily steps.

    3 months

  • Acceptability

    Acceptability will be measured using the mean score of the Intrinsic Motivation Inventory - Interest / Enjoyment Subscale. The scores range from 1 to 7, with higher numbers indicating higher acceptability, and a null value of 5.0.

    3 months

  • Study-Related Adverse Events

    Safety will be assessed as differences in rates of study-related adverse events between GROUP 1 and GROUP 2 during the first three months, when GROUP 1 is in the intervention phase and GROUP 2 is in the non-intervention control phase.

    3 months

Secondary Outcomes (6)

  • Accelerometer-Based Physical Activity

    3 months

  • Late Life Function and Disability Scale, Frequency

    3 months

  • Accelerometer-Based Physical Activity

    6 months

  • Late Life Function and Disability Scale, Frequency

    6 months

  • Late Life Function and Disability Scale, Limitation

    3 months

  • +1 more secondary outcomes

Study Arms (2)

Early PABC Intervention

EXPERIMENTAL

GROUP 1 will participate in the Physical Activity Behavior Change (PABC) intervention phase during the first 3 months. GROUP 1 will then participate in a non-exercise control phase during the second 3 months.

Behavioral: Physical Activity Behavior Change (PABC)

Wait-List Control Intervention

EXPERIMENTAL

GROUP 2 will participate in a non-exercise control phase during the first 3 months. GROUP 2 will then participate in the Physical Activity Behavior Change (PABC) intervention phase in the second 3 months.

Behavioral: Physical Activity Behavior Change (PABC)

Interventions

Home-based weekly sessions (30 min) using behavior change methods for promoting physical activity. Sessions will occur using home-based computer tablets for real-time video interface between the participant and therapist. Participants will wear wrist-mounted activity sensors with direct physical activity feedback during the intervention period to allow for behavioral feedback and action planning.

Early PABC InterventionWait-List Control Intervention

Eligibility Criteria

Age50 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Lower limb amputation 1-5 years prior to enrollment
  • Type 2 Diabetes Mellitus and/or
  • Peripheral Artery Disease
  • Ambulatory using a lower limb prosthesis
  • English speaking

You may not qualify if:

  • Traumatic or cancer-related etiology of the lower limb amputation
  • Unstable heart condition, including:
  • unstable angina
  • uncontrolled cardiac dysrhythmia
  • acute myocarditis
  • acute pericarditis
  • Uncontrolled hypertension
  • Acute systemic infection
  • Prisoner
  • Decisionally challenged volunteers
  • Cancer
  • Recent cerebral vascular accident (within two years)
  • lower extremity wound or ulcer that limits ability to ambulate

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Rocky Mountain Regional VA Medical Center, Aurora, CO

Aurora, Colorado, 80045, United States

Location

Related Publications (1)

  • Christiansen CL, Miller MJ, Kline PW, Fields TT, Sullivan WJ, Blatchford PJ, Stevens-Lapsley JE. Biobehavioral Intervention Targeting Physical Activity Behavior Change for Older Veterans after Nontraumatic Amputation: A Randomized Controlled Trial. PM R. 2020 Oct;12(10):957-966. doi: 10.1002/pmrj.12374. Epub 2020 May 6.

MeSH Terms

Conditions

Diabetes Mellitus, Type 2Peripheral Arterial DiseaseMotor Activity

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesAtherosclerosisArteriosclerosisArterial Occlusive DiseasesVascular DiseasesCardiovascular DiseasesPeripheral Vascular DiseasesBehavior

Results Point of Contact

Title
Cory L. Christiansen
Organization
University of Colorado Denver

Study Officials

  • Cory L. Christiansen, PhD

    Rocky Mountain Regional VA Medical Center, Aurora, CO

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
FED
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 16, 2016

First Posted

April 14, 2016

Study Start

July 1, 2016

Primary Completion

February 22, 2019

Study Completion

February 22, 2019

Last Updated

February 18, 2020

Results First Posted

February 18, 2020

Record last verified: 2020-02

Data Sharing

IPD Sharing
Will not share

Locations