Study to Estimate Radiation Doses and Cancer Risks From Radioactive Fallout From the Trinity Nuclear Test

NCT02734303 | Completed

• 2 other identifiers: 99991608316-C-N083
• Study Type: observational
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

Background: The first nuclear bomb test took place in New Mexico in July 1945. This was called the Trinity test. Researchers want to learn how it affected the health of people who lived in New Mexico at the time of the test. To do this, they want to learn about the diet and daily life of those people at that time. They want to study Native Americans, Hispanic/Latinos, and non-Hispanic/Latino whites. Objective: To learn about the health risks for people who may have been exposed to radiation from the Trinity nuclear test. Eligibility: People who:

• Are Native American, Hispanic/Latino, or non-Hispanic white
• Are age 70 and older
• Lived near the fallout region of the Trinity test and know about lifestyle and dietary patterns in New Mexico in the 1940s and 1950s Design: Participants will be screened with a questionnaire. Participants will answer questions in an interview or a focus group. This will be at a place like an office, tribal or community center, or library. It will take up to 2 hours. The interview or group session will include:
• Questions about their and their family members activities and eating habits in the 1940s and 1950s
• A card-sorting exercise: There will be cards with pictures and names of certain foods. They will sort the cards into 2 piles: those that were consumed and those that were not.
• Filling out a chart of their family members and the foods they ate If participants give permission, their interview or group session will be recorded. ...

Conditions

Cancers

Keywords

Dietary Radioactivity; Dietary Assessment; Retrospective Recall; Focus Group

Outcome Measures

Primary Outcomes (1)

• risk assessment

  prediction of number of excess cancers of: colon, lung, active bone marrow, stomach, and thyroid

  Cumulative since 1945 exposure

Study Arms (1)

Potentially Exposed NM Residents

residents of the state of New Mexico (NM) potentially exposed to radioactive fallout fromthe Trinity nuclear test conducted in 1945

Eligibility Criteria

• Age: 70 Years - 100 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Residents of the state of New Mexico (NM) potentially exposed to radioactive fallout from the Trinity nuclear test conducted in 1945.

You may qualify if:

• Hispanic/Latino, non-Hispanic White or Native American
• years or older (Alive in 1945)
• Resided in New Mexico or on one of New Mexico s tribal reservations (if Native American) during the 1940s and 1950s
• Ideally, helped to care for children in his or her community during the 1940s
• Potential focus group members an d key informants may include any of the following:
• Community elders, tribal members, and people with first hand knowledge of food practices in New Mexico in the 1940s or 1950s.
• Individuals must self-identify as a New Mexico tribal community member, Hispanic/Latino or non-Hispanic white in order to participate
• in an interview, and have firsthand knowledge about lifestyle and dietary patterns in New Mexico during the 1940s or 1950s.

Sponsors & Collaborators

• National Cancer Institute (NCI): lead

Study Sites (1)

University of New Mexico

Albuquerque, New Mexico, 87131, United States

Location

Related Publications (2)

• Simon SL, Bouville A. Radiation doses to local populations near nuclear weapons test sites worldwide. Health Phys. 2002 May;82(5):706-25. doi: 10.1097/00004032-200205000-00016.

  PMID: 12003020 BACKGROUND

• Schwerin M, Schonfeld S, Drozdovitch V, Akimzhanov K, Aldyngurov D, Bouville A, Land C, Luckyanov N, Mabuchi K, Semenova Y, Simon S, Tokaeva A, Zhumadilov Z, Potischman N. The utility of focus group interviews to capture dietary consumption data in the distant past: dairy consumption in Kazakhstan villages 50 years ago. J Dev Orig Health Dis. 2010 Jun;1(3):192-202. doi: 10.1017/S2040174410000243.

  PMID: 24286002 BACKGROUND

MeSH Terms

Conditions

Neoplasms

Study Officials

• Steven L Simon, Ph.D.

  National Cancer Institute (NCI)

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: NIH
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 6, 2016
• First Posted: April 12, 2016
• Study Start: March 17, 2016
• Primary Completion: September 12, 2017
• Study Completion: December 1, 2019
• Last Updated: March 4, 2021

Record last verified: 2021-03

Locations

US (1)