NCT02724462

Brief Summary

The goal of this study is to determine whether the novel smartphone app (SmartQuit) provides higher quit rates than the current standard smoking cessation app.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,503

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2017

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 24, 2016

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 31, 2016

Completed
1.2 years until next milestone

Study Start

First participant enrolled

May 27, 2017

Completed
2.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 27, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 27, 2019

Completed
1 year until next milestone

Results Posted

Study results publicly available

January 5, 2021

Completed
Last Updated

January 5, 2021

Status Verified

November 1, 2020

Enrollment Period

2.6 years

First QC Date

March 24, 2016

Results QC Date

November 12, 2020

Last Update Submit

December 10, 2020

Conditions

Smoking

Keywords

smoking cessationapp for quitting smoking

Outcome Measures

Primary Outcomes (1)

  • 30-day Point Prevalence Abstinence, Complete-case

    Percentage of participants reporting no smoking in the past 30 days, 12 months post-treatment. Participants missing follow-up data are excluded for the complete-case analysis. Exact 2-sided CI was based on the observed proportion of participants.

    12 months post randomization

Secondary Outcomes (1)

  • 30-day Point Prevalence Abstinence, Missing=Smoking Imputation

    12 months post randomization

Study Arms (2)

Experimental

EXPERIMENTAL

This is the experimental arm of the study. This includes receiving the novel/experimental smartphone smoking cessation app. Therapy description withheld to protect the integrity of the study.

Behavioral: Smartphone-delivered Intervention (SmartQuit)

Control

ACTIVE COMPARATOR

This is the control arm of the study. This includes receiving the standard of care smartphone smoking cessation app. Therapy description withheld to protect the integrity of the study.

Behavioral: : Smartphone-delivered Intervention (Standard of care app)

Interventions

Smartphone-delivered Intervention (SmartQuit)BEHAVIORAL

The experimental arm includes an intervention using a novel smartphone smoking cessation app.

Experimental
: Smartphone-delivered Intervention (Standard of care app)BEHAVIORAL

The control intervention uses a standard of care smartphone smoking cessation app.

Control

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • age 18 or older
  • smokes at least five cigarettes daily for at least past 12 months
  • wants to quit cigarette smoking in the next 30 days
  • if concurrently using any other nicotine or tobacco products, wants to quit using them within the next 30 days
  • interested in learning skills to quit smoking
  • willing to be randomly assigned to either condition
  • resides in US
  • has at least daily access to their own personal Apple iPhone, Android, or Windows Phone
  • knows how to login and download a smartphone application
  • willing and able to read in English
  • not using other smoking cessation interventions (including apps or our other intervention studies).
  • willing to complete all three follow-up surveys
  • provide email, phone, and mailing address.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Fred Hutchinson Cancer Research Center

Seattle, Washington, 98109, United States

Location

Related Publications (9)

  • Santiago-Torres M, Mull KE, Sullivan BM, Cupertino AP, Salloum RG, Triplette M, Zvolensky MJ, Bricker JB. Evaluating the Impact of Pharmacotherapy in Augmenting Quit Rates Among Hispanic Adults in an App-Delivered Smoking Cessation Intervention: Secondary Analysis of a Randomized Controlled Trial. JMIR Form Res. 2025 Jan 31;9:e69311. doi: 10.2196/69311.

    PMID: 39889280DERIVED

  • Santiago-Torres M, Mull KE, Sullivan BM, Prochaska JJ, Zvolensky MJ, Bricker JB. Can an Acceptance and Commitment Therapy-Based Smartphone App Help Individuals with Mental Health Disorders Quit Smoking? Depress Anxiety. 2024;2024:1055801. doi: 10.1155/2024/1055801. Epub 2024 Jun 21.

    PMID: 39845432DERIVED

  • Santiago-Torres M, Mull KE, Sullivan BM, Bricker JB. Use of e-Cigarettes in Cigarette Smoking Cessation: Secondary Analysis of a Randomized Controlled Trial. JMIR Mhealth Uhealth. 2023 Nov 9;11:e48896. doi: 10.2196/48896.

    PMID: 37943594DERIVED

  • Jackson S, Brown J, Norris E, Livingstone-Banks J, Hayes E, Lindson N. Mindfulness for smoking cessation. Cochrane Database Syst Rev. 2022 Apr 14;4(4):CD013696. doi: 10.1002/14651858.CD013696.pub2.

    PMID: 35420700DERIVED

  • Santiago-Torres M, Mull KE, Sullivan BM, Ferketich AK, Bricker JB. Efficacy of an acceptance and commitment therapy-based smartphone application for helping rural populations quit smoking: Results from the iCanQuit randomized trial. Prev Med. 2022 Apr;157:107008. doi: 10.1016/j.ypmed.2022.107008. Epub 2022 Mar 4.

    PMID: 35257698DERIVED

  • Santiago-Torres M, Mull KE, Sullivan BM, Kendzor DE, Bricker JB. Efficacy and utilization of smartphone applications for smoking cessation among low-income adults: Secondary analysis of the iCanQuit randomized trial. Drug Alcohol Depend. 2022 Feb 1;231:109258. doi: 10.1016/j.drugalcdep.2021.109258. Epub 2021 Dec 31.

    PMID: 35026491DERIVED

  • Santiago-Torres M, Mull KE, Sullivan BM, Kwon D, Nollen NL, Zvolensky MJ, Bricker JB. Efficacy and utilization of an acceptance and commitment therapy-based smartphone application for smoking cessation among Black adults: secondary analysis of the iCanQuit randomized trial. Addiction. 2022 Mar;117(3):760-771. doi: 10.1111/add.15721. Epub 2021 Dec 9.

    PMID: 34890104DERIVED

  • Bricker JB, Levin M, Lappalainen R, Mull K, Sullivan B, Santiago-Torres M. Mechanisms of Smartphone Apps for Cigarette Smoking Cessation: Results of a Serial Mediation Model From the iCanQuit Randomized Trial. JMIR Mhealth Uhealth. 2021 Nov 9;9(11):e32847. doi: 10.2196/32847.

    PMID: 34751662DERIVED

  • Bricker JB, Watson NL, Mull KE, Sullivan BM, Heffner JL. Efficacy of Smartphone Applications for Smoking Cessation: A Randomized Clinical Trial. JAMA Intern Med. 2020 Nov 1;180(11):1472-1480. doi: 10.1001/jamainternmed.2020.4055.

    PMID: 32955554DERIVED

MeSH Terms

Conditions

SmokingSmoking Cessation

Condition Hierarchy (Ancestors)

BehaviorHealth Behavior

Results Point of Contact

Title
Dr. Jonathan Bricker
Organization
Fred Hutchinson Cancer Research Center
jbricker@fredhutch.org
206-667-5077

Study Officials

  • Jonathan Bricker, Ph.D.

    Fred Hutchinson Cancer Center

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 24, 2016

First Posted

March 31, 2016

Study Start

May 27, 2017

Primary Completion

December 27, 2019

Study Completion

December 27, 2019

Last Updated

January 5, 2021

Results First Posted

January 5, 2021

Record last verified: 2020-11

Data Sharing

IPD Sharing
Will not share

Locations

US(1)