NCT02722889

Brief Summary

Aim of this study is to measure length of the ascending aorta in adults and to investigate the clinical implication of 'elongation' of the aorta.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
298

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2016

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2016

Completed
6 days until next milestone

First Submitted

Initial submission to the registry

March 7, 2016

Completed
23 days until next milestone

First Posted

Study publicly available on registry

March 30, 2016

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2016

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2017

Completed
Last Updated

March 22, 2017

Status Verified

March 1, 2016

Enrollment Period

9 months

First QC Date

March 7, 2016

Last Update Submit

March 20, 2017

Conditions

Thoracic Aorta

Keywords

Ascending aortaElongation of the aortaType A dissectionAortic ruptureAortic length

Outcome Measures

Primary Outcomes (1)

  • Length of the ascending aorta

    Ascending aortic length as measured on computed tomography.

    Up to 72 months

Study Arms (2)

Healthy controls

Healthy control patients

Type A dissection

Patients with proven type A dissection,

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Reference group to assess 'normal' aortic length.

You may qualify if:

  • Underwent recent (\<6 years) contrast-enhanced CT scan which allows for segmentation and assessment of aortic geometry.

You may not qualify if:

  • Age \<18 years old.
  • Prior thoracic, cardiac or aortic surgery.
  • Genetic disease with cardiac and/or aortic involvement (e.g. Marfan's disease).
  • Infectious disease of the aorta.
  • Malignant disease with involvement of heart and/or aorta.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Maastricht University Medical Center

Maastricht, Limburg, 6202AZ, Netherlands

Location

MeSH Terms

Conditions

Aortic Rupture

Condition Hierarchy (Ancestors)

Aneurysm, RupturedAneurysmVascular DiseasesCardiovascular DiseasesAortic AneurysmAortic DiseasesRuptureWounds and Injuries

Study Officials

  • Joachim Wildberger, MD, PhD

    Head of department of Radiology

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 7, 2016

First Posted

March 30, 2016

Study Start

March 1, 2016

Primary Completion

December 1, 2016

Study Completion

January 1, 2017

Last Updated

March 22, 2017

Record last verified: 2016-03

Data Sharing

IPD Sharing
Will not share

Locations

NL(1)