NCT02721836

Brief Summary

The proposed study aims to investigate the feasibility, effectiveness, and perceived benefit of a hatha yoga intervention for patients with irritable bowel syndrome (IBS) compared to nutrition counselling. Further, the potential of both interventions to influence the gut microbiome will be inquired.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
59

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Apr 2016

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 17, 2016

Completed
12 days until next milestone

First Posted

Study publicly available on registry

March 29, 2016

Completed
3 days until next milestone

Study Start

First participant enrolled

April 1, 2016

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2016

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2017

Completed
Last Updated

May 24, 2017

Status Verified

May 1, 2017

Enrollment Period

8 months

First QC Date

March 17, 2016

Last Update Submit

May 23, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Irritable Bowel Syndrome Symptoms

    Irritable Bowel Syndrome Severity Scoring System (IBS-SSS)

    Week 12

Secondary Outcomes (14)

  • disease specific quality of life

    Week 12

  • disease specific quality of life

    Week 24

  • Generic Health-related Quality of life

    Week 12

  • Generic Health-related Quality of life

    Week 24

  • Emotional distress

    Week 12

  • +9 more secondary outcomes

Study Arms (2)

Yoga

EXPERIMENTAL

12 week yoga course, two times a week 75 minutes each time

Behavioral: Yoga

Nutrition

ACTIVE COMPARATOR

3 counselling sessions within 12 weeks

Behavioral: Nutrition Counselling

Interventions

YogaBEHAVIORAL

Yoga intervention 12 weeks, twice weekly 75-minute intervention Yoga postures, breathing, relaxation, and meditation

Yoga

Evidence-based Nutrition Counselling, 3 appointments within 12 weeks

Nutrition

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with irritable bowel syndrome (IBS) diagnosed by physician and confirmed by Rome III diagnostic criteria

You may not qualify if:

  • inflammatory bowel diseases (IBD)
  • total abdominal colectomy
  • no sonographie or colonoscopy as diagnostic criterion
  • stool lactoferrin \> 7mg/g
  • pregnancy or breast feeding
  • simultaneous participation in further clinical intervention trials
  • Regular yoga practice or nutrition counselling in the past 12 months
  • Planned surgery in the study period
  • Serious illness that would interfere with the ability to practice yoga

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Universität Duisburg-Essen

Essen, 45276, Germany

Location

Related Publications (1)

  • Schumann D, Anheyer D, Lauche R, Dobos G, Langhorst J, Cramer H. Effect of Yoga in the Therapy of Irritable Bowel Syndrome: A Systematic Review. Clin Gastroenterol Hepatol. 2016 Dec;14(12):1720-1731. doi: 10.1016/j.cgh.2016.04.026. Epub 2016 Apr 22.

MeSH Terms

Conditions

Irritable Bowel Syndrome

Interventions

Yoga

Condition Hierarchy (Ancestors)

Colonic Diseases, FunctionalColonic DiseasesIntestinal DiseasesGastrointestinal DiseasesDigestive System Diseases

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsSpiritual TherapiesExercise Movement TechniquesPhysical Therapy Modalities

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator, Research fellow

Study Record Dates

First Submitted

March 17, 2016

First Posted

March 29, 2016

Study Start

April 1, 2016

Primary Completion

December 1, 2016

Study Completion

May 1, 2017

Last Updated

May 24, 2017

Record last verified: 2017-05

Data Sharing

IPD Sharing
Will not share

Locations