Phototherapy Applied in Association With Muscular Training

NCT02715050 | Completed DMC

• 1 other identifier: PhD437.894
• Study Type: interventional
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

The effects of phototherapy has been widely studied by some research groups. The investigators know that there are positive results with light application to improve muscle performance and delay fatigue. However, there are few studies showing its´ effects on muscular training. Therefore, the aim of this study was to assess the effects of phototherapy applied at different times during 12 weeks of strength training. For such, 48 volunteers, healthy male, from 18 to 35 years old were recruited to perform a strength training protocol for the anterior muscle of the thigh development. Volunteers performed the training protocol three times a week for 12 weeks. There were assessed isometric peak torque in isokinetic dynamometer, concentric peak torque, 1-repetition maximum test in the leg extension and leg press machines and bilateral thigh perimetry.

Conditions

Muscle Adaptation

Keywords

phototherapy; photobiostimulation; muscle training; muscular adaptation

Outcome Measures

Primary Outcomes (2)

• Change from baseline Maximum voluntary contraction in the isokinetic dynamometer (MVC) at 12 weeks

  Functional performance measure - performed in baseline, 4 weeks, 8 weeks and 12 weeks after the beginning of the muscular training

  12 weeks

• Change from baseline Concentric Torque at 12 weeks

  Functional performance measure - performed in baseline, 4 weeks, 8 weeks and 12 weeks after the beginning of the muscular training

  12 weeks

Secondary Outcomes (1)

• 1-RM test

  12 weeks

Other Outcomes (1)

• Thigh perimetry

  12 weeks

Study Arms (4)

Group A - Active or Placebo Phototherapy

EXPERIMENTAL

Participants enrolled in this group performed a training protocol for 12 weeks with light application before and after the exercise protocol. The phototherapy device was divided in program 1 and program 2. One of these programs consisted in active phototherapy and the other placebo. The subjects allocated in group A, received program 1 before strength training, and the same program 1 after training.

Device: Active or Placebo Phototherapy (MR4)

Group B - Active or Placebo Phototherapy

EXPERIMENTAL

Participants enrolled in this group performed a training protocol for 12 weeks with light application before and after the exercise protocol. The phototherapy device was divided in program 1 and program 2. One of these programs consisted in active phototherapy and the other placebo. The subjects allocated in group B, received program 1 before strength training, and program 2 after training.

Device: Active or Placebo Phototherapy (MR4)

Group C - Active or Placebo Phototherapy

EXPERIMENTAL

Participants enrolled in this group performed a training protocol for 12 weeks with light application before and after the exercise protocol. The phototherapy device was divided in program 1 and program 2. One of these programs consisted in active phototherapy and the other placebo. The subjects allocated in group C, received program 2 before strength training, and program 1 after training.

Device: Active or Placebo Phototherapy (MR4)

Group D - Active or Placebo Phototherapy

EXPERIMENTAL

Participants enrolled in this group performed a training protocol for 12 weeks with light application before and after the exercise protocol. The phototherapy device was divided in program 1 and program 2. One of these programs consisted in active phototherapy and the other placebo. The subjects allocated in group D, received program 2 before strength training, and program 2 after training.

Device: Active or Placebo Phototherapy (MR4)

Interventions

Active or Placebo Phototherapy (MR4) DEVICE

Also known as: MR4 device - device that combines super-pulsed lasers, and red and infrared LEDs (Multi Radiance Medical, Solon, OH, USA)

Group A - Active or Placebo Phototherapy; Group B - Active or Placebo Phototherapy; Group C - Active or Placebo Phototherapy; Group D - Active or Placebo Phototherapy

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• healthy individuals,
• active, that performed less than two exercise sessions per week
• when they presented musculoskeletal injury to the hips or knees in the previous 2 months,
• used pharmacological agents or nutritional supplements regularly, and
• Subjects that did not attend a minimum rate of 80% of all strength training sessions
• Suffered musculoskeletal injury during the ongoing of the study were also excluded.

Sponsors & Collaborators

• University of Nove de Julho: lead
• Fundação de Amparo à Pesquisa do Estado de São Paulo: collaborator

Study Sites (1)

Universidade Nove de Julho

São Paulo, São Paulo, 01504-001, Brazil

Location

Related Publications (3)

• Leal-Junior EC, Vanin AA, Miranda EF, de Carvalho Pde T, Dal Corso S, Bjordal JM. Effect of phototherapy (low-level laser therapy and light-emitting diode therapy) on exercise performance and markers of exercise recovery: a systematic review with meta-analysis. Lasers Med Sci. 2015 Feb;30(2):925-39. doi: 10.1007/s10103-013-1465-4. Epub 2013 Nov 19.

  PMID: 24249354 BACKGROUND

• Seynnes OR, de Boer M, Narici MV. Early skeletal muscle hypertrophy and architectural changes in response to high-intensity resistance training. J Appl Physiol (1985). 2007 Jan;102(1):368-73. doi: 10.1152/japplphysiol.00789.2006. Epub 2006 Oct 19.

  PMID: 17053104 BACKGROUND

• Antonialli FC, De Marchi T, Tomazoni SS, Vanin AA, dos Santos Grandinetti V, de Paiva PR, Pinto HD, Miranda EF, de Tarso Camillo de Carvalho P, Leal-Junior EC. Phototherapy in skeletal muscle performance and recovery after exercise: effect of combination of super-pulsed laser and light-emitting diodes. Lasers Med Sci. 2014 Nov;29(6):1967-76. doi: 10.1007/s10103-014-1611-7. Epub 2014 Jun 19.

  PMID: 24942380 RESULT

Study Officials

• Ernesto Leal-Junior, PhD

  University of Nove de Julho

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Phd researcher

Study Record Dates

• First Submitted: March 11, 2016
• First Posted: March 22, 2016
• Study Start: March 1, 2016
• Primary Completion: August 1, 2016
• Study Completion: October 1, 2016
• Last Updated: October 20, 2016

Record last verified: 2016-10

Locations

BR (1)