Does Glidescope Video Laryngoscope is Related to Less Hemodynamic Response?

NCT02708420 | Completed

• 1 other identifier: GataHRH
• Study Type: interventional
• Target: 70
• Locations: 1 country
• Sites: 1

Brief Summary

Laryngoscopy and endotracheal intubation causes significant hemodynamic response and thus presents an increased risk for patients undergoing cardiac bypass surgery. Prevention or reduction of this increment is important for hemodynamic control. In this randomized single blind study, the aim of this study is to compare the hemodynamic responses of two different laryngoscopy techniques with Glidescope and Macintosh laryngoscope in coronary cardiac bypass surgery patients.

Conditions

Blood Pressure

Keywords

Glidescope; Cardiovascular surgery; Macintosh Laryngoscope; Hemodynamic response; Anesthesia

Outcome Measures

Primary Outcomes (4)

• Change in systolic blood pressure

  invasive blood pressure (mmHg) monitoring

  5 minutes; At start of laryngoscopy and after 30th seconds, 60th seconds, 90th seconds, 120th seconds, 3rd minutes, 4th minutes, 5th minutes

• Change in heart rate

  Heart rate (beats per minute) will be measured before induction, and throughout and after laryngoscopy

  5 minutes; At start of laryngoscopy and after 30th seconds, 60th seconds, 90th seconds, 120th seconds, 3rd minutes, 4th minutes, 5th minutes

• Change in diastolic blood pressure

  invasive blood pressure (mmHg) monitoring

  5 minutes; At start of laryngoscopy and after 30th seconds, 60th seconds, 90th seconds, 120th seconds, 3rd minutes, 4th minutes, 5th minutes

• Change in mean arterial pressure

  invasive blood pressure (mmHg) monitoring

  5 minutes;At start of laryngoscopy and after 30th seconds, 60th seconds, 90th seconds, 120th seconds, 3rd minutes, 4th minutes, 5th minutes

Secondary Outcomes (2)

• Procedure time

  10 minutes

• Cormack lehane laryngoscopic view will be recorded

  10 minutes

Study Arms (2)

Glidescope intubation

OTHER

This standard GlideScope (GS) technique involves a midline laryngoscopy followed by insertion of a styletted endotracheal tube, once an adequate view of the vocal cords is achieved.

Device: Glidescope

Macintosh Laryngoscope

OTHER

This standard technique involves laryngoscopy followed by insertion of a styletted endotracheal tube, once an adequate view of the vocal cords is achieved.

Device: Macintosh Laryngoscope

Interventions

Glidescope DEVICE

This standard GlideScope (GS) technique involves a midline laryngoscopy followed by insertion of a styletted endotracheal tube, once an adequate view of the vocal cords is achieved.

Glidescope intubation

Macintosh Laryngoscope DEVICE

This technique involves a laryngoscopy followed by insertion of a styletted endotracheal tube, once an adequate view of the vocal cords is achieved.

Macintosh Laryngoscope

Eligibility Criteria

• Age: 40 Years - 85 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• American Society of Anesthesiologists (ASA) physical Status 2-3
• Patients undergoing elective cardiac bypass surgery

You may not qualify if:

• Difficult intubation history
• Need for Rapid sequence intubation or alternative intubation method
• Emergency procedures
• Patients that have predictive factors for difficult intubation
• Patients with permanent pacemaker

Sponsors & Collaborators

• Gata Haydarpasa Research Hospital: lead

Study Sites (1)

GATA Haydarpasa Training Hospital

Istanbul, Asia, 34668, Turkey (Türkiye)

Location

Related Publications (9)

• Friedman Z, Gurevich L, Siddiqui N. The effect of a modified GlideScope intubation technique on procedure times, airway morbidity and haemodynamic response. Eur J Anaesthesiol. 2016 Mar;33(3):229-30. doi: 10.1097/EJA.0000000000000339. No abstract available.

  PMID: 26760401 BACKGROUND

• Amini S, Shakib M. Hemodynamic changes following endotracheal intubation in patients undergoing cesarean section with general anesthesia: application of glidescope(R) videolaryngoscope versus direct laryngoscope. Anesth Pain Med. 2015 Mar 30;5(2):e21836. doi: 10.5812/aapm.21836. eCollection 2015 Apr.

  PMID: 25866708 BACKGROUND

• Dashti M, Amini S, Azarfarin R, Totonchi Z, Hatami M. Hemodynamic changes following endotracheal intubation with glidescope((R)) video-laryngoscope in patients with untreated hypertension. Res Cardiovasc Med. 2014 May;3(2):e17598. doi: 10.5812/cardiovascmed.17598. Epub 2014 Apr 1.

  PMID: 25478537 BACKGROUND

• Aqil M. A study of stress response to endotracheal intubation comparing glidescope and flexible fiberoptic bronchoscope. Pak J Med Sci. 2014 Sep;30(5):1001-6. doi: 10.12669/pjms.305.4788.

  PMID: 25225515 BACKGROUND

• Pournajafian AR, Ghodraty MR, Faiz SH, Rahimzadeh P, Goodarzynejad H, Dogmehchi E. Comparing GlideScope Video Laryngoscope and Macintosh Laryngoscope Regarding Hemodynamic Responses During Orotracheal Intubation: A Randomized Controlled Trial. Iran Red Crescent Med J. 2014 Apr;16(4):e12334. doi: 10.5812/ircmj.12334. Epub 2014 Apr 5.

  PMID: 24910788 BACKGROUND

• Maassen RL, Pieters BM, Maathuis B, Serroyen J, Marcus MA, Wouters P, van Zundert AA. Endotracheal intubation using videolaryngoscopy causes less cardiovascular response compared to classic direct laryngoscopy, in cardiac patients according a standard hospital protocol. Acta Anaesthesiol Belg. 2012;63(4):181-6.

  PMID: 23610856 BACKGROUND

• Siddiqui N, Katznelson R, Friedman Z. Heart rate/blood pressure response and airway morbidity following tracheal intubation with direct laryngoscopy, GlideScope and Trachlight: a randomized control trial. Eur J Anaesthesiol. 2009 Sep;26(9):740-5. doi: 10.1097/EJA.0b013e32832b138d.

  PMID: 19417675 BACKGROUND

• Xue FS, Zhang GH, Li XY, Sun HT, Li P, Li CW, Liu KP. Comparison of hemodynamic responses to orotracheal intubation with the GlideScope videolaryngoscope and the Macintosh direct laryngoscope. J Clin Anesth. 2007 Jun;19(4):245-50. doi: 10.1016/j.jclinane.2006.11.004.

  PMID: 17572317 BACKGROUND

• Russell T, Khan S, Elman J, Katznelson R, Cooper RM. Measurement of forces applied during Macintosh direct laryngoscopy compared with GlideScope(R) videolaryngoscopy. Anaesthesia. 2012 Jun;67(6):626-31. doi: 10.1111/j.1365-2044.2012.07087.x. Epub 2012 Feb 21.

  PMID: 22352799 BACKGROUND

Study Officials

• Sezai Ozkan, Prof.

  Gata Haydarpasa Research Hospital

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 27, 2016
• First Posted: March 15, 2016
• Study Start: January 1, 2016
• Primary Completion: May 18, 2017
• Study Completion: June 1, 2017
• Last Updated: June 14, 2017

Record last verified: 2016-03

Locations

TU (1)