NCT02701114

Brief Summary

This study is designed to evaluate pain control of continuous adductor canal blocks placed proximally versus distally within the canal. The investigators hypothesize that there will be similar pain control between both groups.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
76

participants targeted

Target at P50-P75 for not_applicable postoperative-pain

Timeline
Completed

Started Feb 2016

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2016

Completed
28 days until next milestone

First Submitted

Initial submission to the registry

February 29, 2016

Completed
8 days until next milestone

First Posted

Study publicly available on registry

March 8, 2016

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2016

Completed
Last Updated

July 13, 2017

Status Verified

July 1, 2017

Enrollment Period

9 months

First QC Date

February 29, 2016

Last Update Submit

July 11, 2017

Conditions

Post-Operative Pain

Outcome Measures

Primary Outcomes (1)

  • Opioid Consumption (IV Morphine Equivalents)

    Total opioid consumption

    24 Hours

Secondary Outcomes (4)

  • Opioid Consumption (IV Morphine Equivalents)

    48 Hours

  • Pain (Numeric Rating)

    48 Hours

  • Quadriceps Strength (% of Baseline)

    48 Hours

  • Distance Ambulated (Feet)

    48 Hours

Study Arms (2)

Proximal

ACTIVE COMPARATOR

Proximal Adductor Canal Block

Procedure: Proximal Adductor Canal Block

Distal

ACTIVE COMPARATOR

Distal Adductor Canal Block

Procedure: Distal Adductor Canal Block

Interventions

Proximal Adductor Canal BlockPROCEDURE

Continuous Nerve Block

Proximal
Distal Adductor Canal BlockPROCEDURE

Continuous Nerve Block

Distal

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Unilateral Total Knee Arthroplasty
  • ASA physical status I-III
  • \>18 years old
  • Non-pregnant
  • Consent to participate in the study

You may not qualify if:

  • Refusal to participate
  • \<18 years old
  • Chronic opioid use
  • Localized infection Pregnancy Pre-existing coagulopathy Allergy to ultrasound gel or local anesthetics Contraindication to or refusal of spinal anesthetic

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Virginia Mason Medical Center

Seattle, Washington, 98101, United States

Location

Related Publications (1)

  • Meier AW, Auyong DB, Yuan SC, Lin SE, Flaherty JM, Hanson NA. Comparison of Continuous Proximal Versus Distal Adductor Canal Blocks for Total Knee Arthroplasty: A Randomized, Double-Blind, Noninferiority Trial. Reg Anesth Pain Med. 2018 Jan;43(1):36-42. doi: 10.1097/AAP.0000000000000692.

    PMID: 29140959DERIVED

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and Symptoms

Study Officials

  • Neil A Hanson, MD

    Virginia Mason Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Staff Anesthesiologist

Study Record Dates

First Submitted

February 29, 2016

First Posted

March 8, 2016

Study Start

February 1, 2016

Primary Completion

November 1, 2016

Study Completion

November 1, 2016

Last Updated

July 13, 2017

Record last verified: 2017-07

Locations

US(1)