NCT02692612

Brief Summary

The purpose of this project is to investigate the age-related differences in force-velocity muscle characteristics during isolated knee extensions variable in speed and load, during cyclic movements on a usual and recumbent bike variable in speed and velocity development and a functional test battery with healthy participants aged between 20-80 years.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
98

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Feb 2016

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 4, 2015

Completed
3 months until next milestone

Study Start

First participant enrolled

February 1, 2016

Completed
25 days until next milestone

First Posted

Study publicly available on registry

February 26, 2016

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2016

Completed
Last Updated

May 19, 2022

Status Verified

May 1, 2022

Enrollment Period

5 months

First QC Date

November 4, 2015

Last Update Submit

May 18, 2022

Conditions

Sarcopenia

Outcome Measures

Primary Outcomes (1)

  • Differences in power-velocity characteristics during ageing

    peak power and rate of power development (slope) at different velocities during knee extension movement and cyclic multijoint leg press movement compared between young and old people

    1x at baseline (cross sectional study)

Secondary Outcomes (3)

  • Reliability of strength tests on regular and recumbent bike.

    1x at baseline (cross sectional study)

  • Differences in muscle fascicle characteristics during ageing.

    1x at baseline (cross sectional study)

  • Differences in muscle activation during ageing.

    1x at baseline (cross sectional study)

Study Arms (3)

Young

Middle-Aged

Old

Eligibility Criteria

Age20 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

young (20-40y) middle-aged (40-60y) old (60-80y)

You may qualify if:

  • healthy volunteers age 20 to 80 years

You may not qualify if:

  • Knee or hip prothesis
  • Systematic training
  • Cardiovascular disease
  • Acute lower back pain
  • Acute knee pain
  • Dementia

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of kinesiology and rehabilitation sciences

Leuven, 3000, Belgium

Location

MeSH Terms

Conditions

Sarcopenia

Condition Hierarchy (Ancestors)

Muscular AtrophyNeuromuscular ManifestationsNeurologic ManifestationsNervous System DiseasesAtrophyPathological Conditions, AnatomicalPathological Conditions, Signs and SymptomsSigns and Symptoms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 4, 2015

First Posted

February 26, 2016

Study Start

February 1, 2016

Primary Completion

July 1, 2016

Study Completion

July 1, 2016

Last Updated

May 19, 2022

Record last verified: 2022-05

Locations

BE(1)