NCT02688725

Brief Summary

Currently, there is no standard recommendation for using imaging studies to check patients for breast cancer recurrence who have been treated with mastectomy. The investigator proposes performing in-office ultrasound examinations of these patients to determine if this would be helpful in identifying an expected 5-7% of patients with breast cancer recurrences following mastectomy.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for not_applicable breast-cancer

Timeline
Completed

Started Dec 2014

Longer than P75 for not_applicable breast-cancer

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2014

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

December 29, 2015

Completed
2 months until next milestone

First Posted

Study publicly available on registry

February 23, 2016

Completed
3.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2019

Completed
Last Updated

August 28, 2019

Status Verified

August 1, 2019

Enrollment Period

5 years

First QC Date

December 29, 2015

Last Update Submit

August 27, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • To determine the number of breast cancer recurrences following mastectomy detected by surgeon-performed ultrasound.

    To determine the number of breast cancer recurrences following mastectomy detected by surgeon-performed ultrasound during a three year trial period.

    3 years

Secondary Outcomes (1)

  • The sensitivity of surgeon performed breast ultrasound to detect breast cancer recurrence after mastectomy will be measured.

    3 years

Study Arms (1)

Ultrasound

EXPERIMENTAL

post mastectomy ultrasound

Device: post mastectomy ultrasound

Interventions

post mastectomy ultrasound

Ultrasound

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • must be ≥ 18 years of age.
  • histologic diagnosis of invasive (ductal or lobular) or in situ (ductal) breast cancer (American Joint Committee on Cancer, 7th edition stage 0, I, II, III, or IV) -previously treated with mastectomy

You may not qualify if:

  • pregnant or breast feeding.
  • cannot tolerate lying supine for breast ultrasound examination.
  • mastectomy for lobular carcinoma in situ, atypical ductal hyperplasia, or extensive microcalcifications in the absence of concurrent DCIS or invasive breast cancer

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Providence Regional Cancer Partnership

Everett, Washington, 98201, United States

Location

MeSH Terms

Conditions

Breast Neoplasms

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsBreast DiseasesSkin DiseasesSkin and Connective Tissue Diseases

Study Officials

  • Steve Martinez, MD, MAS,FACS

    Providence Health & Services

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
SCREENING
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 29, 2015

First Posted

February 23, 2016

Study Start

December 1, 2014

Primary Completion

December 1, 2019

Study Completion

December 1, 2019

Last Updated

August 28, 2019

Record last verified: 2019-08

Data Sharing

IPD Sharing
Will not share

Locations