NCT02686905

Brief Summary

The objectives in this study are to provide information on the efficacy of transdermal supplement patches on treating nutrient malabsorption and deficiency in post-op bariatric patients, and to determine short-term body composition, HbA1c and fasting plasma glucose outcomes for patients after bariatric surgery.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2016

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2016

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

February 4, 2016

Completed
18 days until next milestone

First Posted

Study publicly available on registry

February 22, 2016

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2017

Completed
Last Updated

September 30, 2016

Status Verified

September 1, 2016

Enrollment Period

1.4 years

First QC Date

February 4, 2016

Last Update Submit

September 29, 2016

Conditions

Outcome Measures

Primary Outcomes (11)

  • Fasting Blood Glucose

    Glucose (mg/dL)

    3 months

  • Calcium Blood Value

    Calcium (mg/dL)

    3 months

  • Iron Blood Value

    Ferritin (ng/mL)

    3 months

  • Vitamin B12 Blood Value

    B12 (pg/mL)

    3 months

  • Vitamin D Blood Value

    Vitamin D, 25-Hydroxy (pg/mL)

    3 months

  • HbA1c Blood Value

    Hemoglobin A1c (%)

    3 months

  • Fat Mass Measurement

    Fat Mass (kg) via Tanita scale measurements

    3 months

  • Fat Free Mass Measurement

    Fat Free Mass (kg) via Tanita scale measurements

    3 months

  • Weight Measurement

    Weight (kg) via Tanita scale measurements

    3 months

  • Waist Circumference

    Waist circumference (cm)

    3 months

  • Hip Circumference

    Hip circumference (cm)

    3 months

Secondary Outcomes (2)

  • Height

    3 months

  • Total Body Water

    3 months

Study Arms (2)

Topical vitamin patch

EXPERIMENTAL

Dietary Supplement: PatchMD Vitamin D3/Calcium Patch Dietary Supplement: PatchMD Multivitamin Patch Dietary Supplement: PatchMD B12 Energy Plus Patch

Dietary Supplement: PatchMD Vitamin D3/Calcium PatchDietary Supplement: PatchMD Multivitamin PatchDietary Supplement: PatchMD B12 Energy Plus Patch

Oral vitamins

EXPERIMENTAL

Dietary Supplement: Chewable Multivitamin with Iron Dietary Supplement: Chewable Calcium Dietary Supplement: Quick Dissolve B12

Dietary Supplement: Chewable Multivitamin with IronDietary Supplement: Chewable CalciumDietary Supplement: Quick Dissolve B12

Interventions

Take daily: Chewable Multivitamin with Iron. The chewable vitamins, vitamin chew, or vitamin rapid/quick-melts can be consumed after surgery when cleared by the surgeon.

Also known as: Oral Vitamin Supplementation
Oral vitamins

Wear daily: PatchMD Vitamin D3/Calcium patch. The patch can be worn immediately after surgery in order to prevent deficiencies, and we hope to show that this supplementation method can also promote lean muscle mass retention. In addition, due to the malabsorptive properties of bariatric surgery, we hope to show that patients will be more likely to completely absorb the micronutrient via transdermal application than through oral intake.

Also known as: Transdermal Vitamin Supplementation
Topical vitamin patch
PatchMD Multivitamin PatchDIETARY_SUPPLEMENT

Wear daily: PatchMD Multivitamin patch. The patch can be worn immediately after surgery in order to prevent deficiencies, and we hope to show that this supplementation method can also promote lean muscle mass retention. In addition, due to the malabsorptive properties of bariatric surgery, we hope to show that patients will be more likely to completely absorb the micronutrient via transdermal application than through oral intake.

Also known as: Transdermal Vitamin Supplementation
Topical vitamin patch

Wear daily: PatchMD B12 Energy Plus patch. The patch can be worn immediately after surgery in order to prevent deficiencies, and we hope to show that this supplementation method can also promote lean muscle mass retention. In addition, due to the malabsorptive properties of bariatric surgery, we hope to show that patients will be more likely to completely absorb the micronutrient via transdermal application than through oral intake.

Also known as: Transdermal Vitamin Supplementation
Topical vitamin patch
Chewable CalciumDIETARY_SUPPLEMENT

Take daily: Chewable Calcium. The chewable vitamins, vitamin chew, or vitamin rapid/quick-melts can be consumed after surgery when cleared by the surgeon.

Also known as: Oral Vitamin Supplementation
Oral vitamins
Quick Dissolve B12DIETARY_SUPPLEMENT

Take daily: Quick Dissolve B12. The chewable vitamins, vitamin chew, or vitamin rapid/quick-melts can be consumed after surgery when cleared by the surgeon.

Also known as: Oral Vitamin Supplementation
Oral vitamins

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • patients currently approved for vertical sleeve or gastric bypass bariatric surgery
  • female patients should not be pregnant or plan to become pregnant

You may not qualify if:

  • metal objects in the body
  • current weight greater than 600lbs
  • previous bariatric (revision) surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Oliak Center for Weight Loss

Brea, California, 92821, United States

RECRUITING

MeSH Terms

Conditions

Avitaminosis

Interventions

IronTransdermal PatchCalcium Carbonate

Condition Hierarchy (Ancestors)

Deficiency DiseasesMalnutritionNutrition DisordersNutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Metals, HeavyElementsInorganic ChemicalsTransition ElementsMetalsEquipment and SuppliesCalcium CompoundsCarbonatesCarbonic AcidCarbon Compounds, InorganicMinerals

Study Officials

  • Bonny Burns-Whitmore, DrPH, RD

    Cal Poly Pomona

    STUDY DIRECTOR
  • David M Oliak, MD

    Oliak Center for Weight Loss

    STUDY CHAIR

Central Study Contacts

Rebecca McDorman, BS

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Graduate Student

Study Record Dates

First Submitted

February 4, 2016

First Posted

February 22, 2016

Study Start

January 1, 2016

Primary Completion

June 1, 2017

Study Completion

June 1, 2017

Last Updated

September 30, 2016

Record last verified: 2016-09

Data Sharing

IPD Sharing
Will not share

Locations