Spinal Aesthesia in Women With Placenta Previa Percreta

NCT02686242 | Completed DMC

• 1 other identifier: XJH-A-2015-6-6-01
• Study Type: observational
• Target: 68
• Locations: 1 country
• Sites: 1

Brief Summary

Placenta previa percreta is a dangerous complication during surgery. Due to the high risk of hemorrhage, most parturients with placenta previa have to accept cesarean section. In this study investigators compare the effect of different anesthetic techniques on these patients.

Conditions

Complications; Cesarean Section

Keywords

cesarean section; spinal anesthesia; general anesthesia

Outcome Measures

Primary Outcomes (1)

• incidence of hypotension

  from beginning of the surgery to the end of the surgery,approximately 1 hour

Secondary Outcomes (4)

• usage of norepinephrine

  from beginning of the surgery to the end of the surgery,approximately 1 hour

• dose of norepinephrine

  from beginning of the surgery to the end of the surgery,approximately 1 hour

• lowest systemic blood pressure

  from beginning of the surgery to the end of the surgery,approximately 1 hour

• maximal decrease of systemic blood pressure

  from beginning of the surgery to the end of the surgery,approximately 1 hour

Study Arms (2)

spinal anesthesia

patients receive spinal anesthesia before general anesthesia

Procedure: spinal anesthesia

general anesthesia

patients receive general anesthesia

Procedure: general anesthesia

Interventions

spinal anesthesia PROCEDURE

bupivacaine injected by spinal puncture

spinal anesthesia

general anesthesia PROCEDURE

general anesthesia with intubation

general anesthesia

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

parturients with placenta praevia/accreta scheduled for cesarean section

You may qualify if:

• women with placenta previa and increta-percreta (diagnosed by ultrasound and/or magnetic resonance imaging and confirmed during cesarean section)
• women accepted cesarean section

You may not qualify if:

• women with baseline systemic blood pressure higher than 180 mmHg
• women with coagulation disorder

Sponsors & Collaborators

• Air Force Military Medical University, China: lead

Study Sites (1)

Xijing Hospital, Fourth Military Medical University

Xi'an, Shaanxi, 710032, China

Location

Related Publications (3)

• Kocaoglu N, Gunusen I, Karaman S, Ergenoglu AM, Firat V. Management of anesthesia for cesarean section in parturients with placenta previa with/without placenta accreta: a retrospective study. Ginekol Pol. 2012 Feb;83(2):99-103.

  PMID: 22568353 BACKGROUND

• Ioscovich A, Mirochnitchenko E, Halpern S, Samueloff A, Grisaru-Granovsky S, Gozal Y, Einav S. Perioperative anaesthetic management of high-order repeat caesarean section: audit of practice in a university-affiliated medical centre. Int J Obstet Anesth. 2009 Oct;18(4):314-9. doi: 10.1016/j.ijoa.2009.01.014. Epub 2009 Aug 7.

  PMID: 19665365 BACKGROUND

• Mok M, Heidemann B, Dundas K, Gillespie I, Clark V. Interventional radiology in women with suspected placenta accreta undergoing caesarean section. Int J Obstet Anesth. 2008 Jul;17(3):255-61. doi: 10.1016/j.ijoa.2007.11.010. Epub 2008 Jun 2.

  PMID: 18513942 BACKGROUND

MeSH Terms

Interventions

Anesthesia, Spinal; Anesthesia, General

Intervention Hierarchy (Ancestors)

Anesthesia, Conduction; Anesthesia; Anesthesia and Analgesia

Study Officials

• Hailong Dong

  Xijing hosptial

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr.

Study Record Dates

• First Submitted: January 13, 2016
• First Posted: February 19, 2016
• Study Start: December 1, 2015
• Primary Completion: March 1, 2016
• Study Completion: March 1, 2016
• Last Updated: June 22, 2016

Record last verified: 2016-06

Locations

CN (1)