Factors and Perceptions Affecting Treatment Choices of Breast Cancer Patients

NCT02679638 | Unknown DMC

• 1 other identifier: 27-15
• Study Type: observational
• Target: 450
• Locations: 0 countries
• Sites: N/A

Brief Summary

A Multi-center Cross-sectional quantitative study with a preliminary qualitative study part aiming to identify and analyze demand factors, supply factors and perceptions affecting Breast Cancer patients' treatment choices of Breast Cancer patients in 5 key decision points: participation role in the decision making process, hospital choice, treatment regimen choice, surgical extent and surgeon choice. 25 patients and caregivers will participate in the qualitative part and 425 Israeli Breast Cancer patients will participate in the quantitative study.

Conditions

Breast Cancer

Keywords

breast cancer; treatment choice; factor; perception

Outcome Measures

Primary Outcomes (5)

• Proportion of active, collaborative and passive patients according to the Control Preferences Scale

  According to the Control Preferences Scale, a questionnaire developed by Degner and Colleagues (Degner, 1997), patients can take fully active role in the treatment decision process or be mostly active, collaborative, mostly passive or fully passive. The study will look at the factors and perceptions affecting patient's decision role.

  Through study completion, an average of 18 months.

• Large or small hospital choice

  The study interviews patients treated at two large Hospitals (Rambam, Sheba), and two small hospitals (Kaplan, Barzilay) looking for the factors and perceptions affecting large or small hospital choice.

  Through study completion, an average of 18 months.

• Proportion of patients who chose an oncological regimen more intense than recommended by clinical guidelines.

  The study will look at the factors and perceptions affecting patient's choice to undergo an oncological treatment more intense than recommended by clinical guidelines.

  Through study completion, an average of 18 months.

• Proportion of patients choosing radical mastectomy over lumpectomy

  The study will look at the factors and perceptions affecting patient's choice to undergo a surgical cancer removal procedure more radical than recommended by clinical guidelines.

  Through study completion, an average of 18 months.

• Specific surgeon choice

  The study will look at the factors and perceptions affecting patient's choice a specific surgeon in the Israeli healthcare system.

  Through study completion, an average of 18 months.

Study Arms (4)

Kaplan Hospital

Breast cancer survivors recruited at the Kaplan Medical Center

Other: Factors and perceptions questionnaire; Other: Qualitative interview

Rambam Hospital

Breast cancer survivors recruited at the Rambam Medical Center

Other: Factors and perceptions questionnaire; Other: Qualitative interview

Sheba

Breast cancer survivors recruited at the Sheba Medical Center

Other: Factors and perceptions questionnaire

Barzilai

Breast cancer survivors recruited at the Barzilai Medical Center

Other: Factors and perceptions questionnaire

Interventions

Factors and perceptions questionnaire OTHER

A detailed questionnaire inquiring about demand factors, supply factors and perceptions affecting patients' treatment choices in 5 key decision points: participation role in the decision making process, hospital choice, treatment regimen choice, surgical extent and surgeon choice.

Barzilai; Kaplan Hospital; Rambam Hospital; Sheba

Qualitative interview OTHER

Depth interviews with 20 breast cancer patients, 2 spouses and 3 staff members.

Kaplan Hospital; Rambam Hospital

Eligibility Criteria

• Age: 30 Years - 75 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Hebrew speaking Jewish women aged 30 - 75 years, diagnosed with breast cancer up to 5 years prior to study recruitment, which have successfully completed all chemotherapy and radiotherapy treatments and are considered disease free.

You may qualify if:

• Hebrew speaking Jewish women
• Aged 30 - 75 years
• Diagnosed with breast cancer up to 5 years prior to study recruitment
• Successfully completed all chemotherapy and radiotherapy treatments
• Considered Cancer free

You may not qualify if:

• Any type of residual cancer
• Any type of chemotherapy or radiotherapy

Sponsors & Collaborators

• University of Haifa: lead

Related Publications (16)

• Adams EK, Houchens R, Wright GE, Robbins J. Predicting hospital choice for rural Medicare beneficiaries: the role of severity of illness. Health Serv Res. 1991 Dec;26(5):583-612.

  PMID: 1743970 RESULT

• Beaver K, Luker KA, Owens RG, Leinster SJ, Degner LF, Sloan JA. Treatment decision making in women newly diagnosed with breast cancer. Cancer Nurs. 1996 Feb;19(1):8-19. doi: 10.1097/00002820-199602000-00002.

  PMID: 8904382 RESULT

• Benbassat J, Pilpel D, Tidhar M. Patients' preferences for participation in clinical decision making: a review of published surveys. Behav Med. 1998 Summer;24(2):81-8. doi: 10.1080/08964289809596384.

  PMID: 9695899 RESULT

• Bouche G, Migeot V, Mathoulin-Pelissier S, Salamon R, Ingrand P. Breast cancer surgery: do all patients want to go to high-volume hospitals? Surgery. 2008 Jun;143(6):699-705. doi: 10.1016/j.surg.2008.03.013. Epub 2008 May 9.

  PMID: 18549885 RESULT

• Celaya MO, Rees JR, Gibson JJ, Riddle BL, Greenberg ER. Travel distance and season of diagnosis affect treatment choices for women with early-stage breast cancer in a predominantly rural population (United States). Cancer Causes Control. 2006 Aug;17(6):851-6. doi: 10.1007/s10552-006-0025-7.

  PMID: 16783613 RESULT

• Duric V, Stockler M. Patients' preferences for adjuvant chemotherapy in early breast cancer: a review of what makes it worthwhile. Lancet Oncol. 2001 Nov;2(11):691-7. doi: 10.1016/S1470-2045(01)00559-9.

  PMID: 11902540 RESULT

• Harris KM. How do patients choose physicians? Evidence from a national survey of enrollees in employment-related health plans. Health Serv Res. 2003 Apr;38(2):711-32. doi: 10.1111/1475-6773.00141.

  PMID: 12785569 RESULT

• Hawley ST, Griggs JJ, Hamilton AS, Graff JJ, Janz NK, Morrow M, Jagsi R, Salem B, Katz SJ. Decision involvement and receipt of mastectomy among racially and ethnically diverse breast cancer patients. J Natl Cancer Inst. 2009 Oct 7;101(19):1337-47. doi: 10.1093/jnci/djp271. Epub 2009 Aug 31.

  PMID: 19720966 RESULT

• Jansen SJ, Otten W, Stiggelbout AM. Review of determinants of patients' preferences for adjuvant therapy in cancer. J Clin Oncol. 2004 Aug 1;22(15):3181-90. doi: 10.1200/JCO.2004.06.109.

  PMID: 15284271 RESULT

• Katz SJ, Lantz PM, Janz NK, Fagerlin A, Schwartz K, Liu L, Deapen D, Salem B, Lakhani I, Morrow M. Patient involvement in surgery treatment decisions for breast cancer. J Clin Oncol. 2005 Aug 20;23(24):5526-33. doi: 10.1200/JCO.2005.06.217.

  PMID: 16110013 RESULT

• Keating NL, Guadagnoli E, Landrum MB, Borbas C, Weeks JC. Treatment decision making in early-stage breast cancer: should surgeons match patients' desired level of involvement? J Clin Oncol. 2002 Mar 15;20(6):1473-9. doi: 10.1200/JCO.2002.20.6.1473.

  PMID: 11896094 RESULT

• Nelson JA, Tchou J, Domchek S, Sonnad SS, Serletti JM, Wu LC. Breast reconstruction in bilateral prophylactic mastectomy patients: factors that influence decision making. J Plast Reconstr Aesthet Surg. 2012 Nov;65(11):1481-9. doi: 10.1016/j.bjps.2012.05.001. Epub 2012 May 27.

  PMID: 22640643 RESULT

• Rees CE, Bath PA. The information needs and source preferences of women with breast cancer and their family members: a review of the literature published between 1988 and 1998. J Adv Nurs. 2000 Apr;31(4):833-41. doi: 10.1046/j.1365-2648.2000.01341.x.

  PMID: 10759979 RESULT

• Simes RJ, Coates AS. Patient preferences for adjuvant chemotherapy of early breast cancer: how much benefit is needed? J Natl Cancer Inst Monogr. 2001;(30):146-52. doi: 10.1093/oxfordjournals.jncimonographs.a003453.

  PMID: 11773309 RESULT

• Tropman SE, Ricketts TC, Paskett E, Hatzell TA, Cooper MR, Aldrich T. Rural breast cancer treatment: evidence from the Reaching Communities for Cancer Care (REACH) project. Breast Cancer Res Treat. 1999 Jul;56(1):59-66. doi: 10.1023/a:1006279117650.

  PMID: 10517343 RESULT

• Degner LF, Sloan JA, Venkatesh P. The Control Preferences Scale. Can J Nurs Res. 1997 Fall;29(3):21-43.

  PMID: 9505581 RESULT

MeSH Terms

Conditions

Breast Neoplasms

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Breast Diseases; Skin Diseases; Skin and Connective Tissue Diseases

Study Officials

• Shuli Brammli-Greenberg, PhD

  Head of the Master of Public Health Program at Haifa University

  STUDY CHAIR

Central Study Contacts

Shuli Brammli-Greenberg, PhD

CONTACT

+972508159054; Shuli@jdc.org.il

Boaz Hovav, MD

CONTACT

+972543166653; bhovav@campus.haifa.ac.il

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 4, 2016
• First Posted: February 10, 2016
• Study Start: February 1, 2016
• Primary Completion: February 1, 2017
• Study Completion: May 1, 2017
• Last Updated: February 10, 2016

Record last verified: 2016-02

Data Sharing

• IPD Sharing: Will not share