Young Women's Health CoOp (Cooperative) in Cape Town
YWHC
Seek, Test, Treat, & Retain Pilot for Out of School Teens at Risk in Cape Town
1 other identifier
interventional
100
1 country
1
Brief Summary
This supplement study is an adaptation of the larger NIH-funded parent study, the Women's Health CoOp+, which tests a combination biobehavioral HIV prevention approach to enhance standard HIV testing practices for alcohol and drug (AOD)-using women across the city of Pretoria, South Africa. The current supplemental study seeks to reach AOD-using female adolescents who experience the greatest burden of new HIV infections and are currently underserved by HIV and drug-treatment programs in Cape Town, South Africa and test the validation of both the instrument and adapted intervention.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable hiv
Started May 2014
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2014
CompletedFirst Submitted
Initial submission to the registry
January 19, 2016
CompletedFirst Posted
Study publicly available on registry
February 9, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2016
CompletedJanuary 8, 2025
January 1, 2025
1.9 years
January 19, 2016
January 6, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Unprotected intercourse among women
Percentages of condom use at last sex
One month post-intervention
Secondary Outcomes (7)
Alcohol use
One month post-intervention
Alcohol use
One month post-intervention
Substance use
One month post-intervention
Substance use
One month post-intervention
Victimization
One month post-intervention
- +2 more secondary outcomes
Study Arms (2)
Young Women's Health CoOp (YWHC)
EXPERIMENTALThis is an adapted behavioral intervention for young women in Cape Town South Africa who dropped out of school, who use alcohol and other drugs and are at risk for HIV.
HIV Counseling/Testing
ACTIVE COMPARATORProvide age and gender appropriate standard HIV counseling and testing.
Interventions
Participants in this group will participate in two workshops of the young woman-focused intervention about HIV/STIs (sexually transmitted infections), sexual behaviors, alcohol and other drug use, violence, communication skills, and other issues. Participants will develop personalized risk reduction action plans at the end of each workshop session.
Participants will be tested for HIV and if positive will receive counseling in accordance with national standards.
Eligibility Criteria
You may qualify if:
- Female, 16 to 21 years of age
- Dropped out of school for at least 6 months
- Currently dropped out of school
- Have not completed matric or N 3 certificate
- Have used at least one drug (which can include alcohol) at least weekly in the past 90 days
- Report unprotected sex with a male partner in the last 90 days
- Able to provide informed assent to participate or informed consent if at least 18 years old
- Live in a targeted community Delft, Khayelitsha, or Mfuleni
You may not qualify if:
- Have been a part of formative activities
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- RTI Internationallead
- Medical Research Council, South Africacollaborator
Study Sites (1)
RTI International
Research Triangle Park, North Carolina, 27709, United States
Related Publications (1)
Carney T, Browne FA, Myers B, Kline TL, Howard B, Wechsberg WM. Adolescent female school dropouts who use drugs and engage in risky sex: effects of a brief pilot intervention in Cape Town, South Africa. AIDS Care. 2019 Jan;31(1):77-84. doi: 10.1080/09540121.2018.1500008. Epub 2018 Jul 18.
PMID: 30021470DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Felicia Browne, ScD
RTI International
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
January 19, 2016
First Posted
February 9, 2016
Study Start
May 1, 2014
Primary Completion
April 1, 2016
Study Completion
April 1, 2016
Last Updated
January 8, 2025
Record last verified: 2025-01
Data Sharing
- IPD Sharing
- Will share
After the main findings are published, we welcome other researchers who want to analyze the data in other ways. Before this time, however, we anticipate establishing a publication plan that involves other researchers and institutions. Analytic data sets will be prepared in accordance with the "Privacy Rule" of the Health Insurance Portability and Accountability Act (HIPAA; http://www.hhs.gov/ocr/) as "limited data sets" in which names and other personal health identifiers are removed, birthdays have been converted to age at intake, and other dates have been changed to be days before or after the date of intake.