Effect of Hookworm Elimination and Vitamin A Intervention on Iron Status of Preschool Children in Sichuan, China
Chengdu Women's and Children's Central Hospital
1 other identifier
interventional
209
0 countries
N/A
Brief Summary
The present study is intended to supplement the preschool anemic children with vitamin A capsule and de-hookworm administration in poverty Sichuan province. We eventually expect our study can provide a cost-effective, safe and more beneficial public health strategy to manage the anemia status of preschool children in poverty area.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for phase_4
Started Mar 2012
Typical duration for phase_4
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2014
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2015
CompletedFirst Submitted
Initial submission to the registry
August 28, 2015
CompletedFirst Posted
Study publicly available on registry
February 5, 2016
CompletedFebruary 5, 2016
February 1, 2016
2.5 years
August 28, 2015
February 4, 2016
Conditions
Outcome Measures
Primary Outcomes (1)
Hemoglobin concentration
six month
Study Arms (3)
ZENTEL
EXPERIMENTALChildren in intervention group 1 was received 400 mg single-dose albendazole administration, by mouth, for once.
ZENTEL and Vitamin A Soft Capsules
EXPERIMENTALChildren in intervention group 2 was received a 200,000 IU vitamin A capsule combined 400 mg single-dose albendazole once initially, by mouth.
No drug adminitrated
NO INTERVENTIONChildren in this Group were received no intervention as control group
Interventions
Children in Group 2 (n=62) received 400 mg single-dose albendazole (helmintic treatment)
Children in Group 3 (n=60) received a 200,000 IU vitamin A capsule combined with 400 mg single-dose albendazole once initially
Eligibility Criteria
You may qualify if:
- Apparent health
- Hb concentration \<110 g/l but not \<80 g/l
- C-reaction protein (CRP) \<10 mg/L
- Parental or guardian approval of participation in all aspects of the study
- Parental/guardian agreement to avoid the additional use of vitamin and mineral supplements and de-hookworm administration during the trial.-
You may not qualify if:
- \) Children with Hb\<80 g/l and /or CRP \>10 mg/l were sent to hospital with special treatment
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- phase 4
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- chief
Study Record Dates
First Submitted
August 28, 2015
First Posted
February 5, 2016
Study Start
March 1, 2012
Primary Completion
September 1, 2014
Study Completion
March 1, 2015
Last Updated
February 5, 2016
Record last verified: 2016-02
Data Sharing
- IPD Sharing
- Will share
It is my pleasure to share some data with other researcher who are interested in this theme.