Ionized Magnesium in Athletes

NCT02674789 | Unknown

• 1 other identifier: NL54333.081.15
• Study Type: interventional
• Target: 18
• Locations: 0 countries
• Sites: N/A

Brief Summary

Ionized magnesium variation is measured during a normal day and again during a day with an exercise protocol of 90 minutes.

Conditions

Magnesium Deficiency

Keywords

Exercise; Athletes; Ionized Magnesium; Variation; Blood

Outcome Measures

Primary Outcomes (1)

• Blood samples analyzed on the pHOx analyzer for their ionized magnesium concentration

  blood

  Blood samples are collected at 7 set time points during one day

Secondary Outcomes (1)

• blood samples are analyzed on the Dimension Vista 1500 of Siemens for their total magnesium concentration

  Blood samples are collected at 7 set time points during one day

Study Arms (2)

Exercise day

EXPERIMENTAL

Behavioral intervention: 90min bike ergometer test at 70% of VO2max. Blood samples are collected at set time points (08:30, 11:00, 12:30, 13:30, 15:00, 16:00 and 18:30). Blood samples are analyzed on the pHOx analyzer for their ionized magnesium concentration. And on the Dimension Vista 1500 from Siemens for their total magnesium concentration.

Behavioral: Exercise protocol

Non exercise day (Rest day)

NO INTERVENTION

No exercise protocol. Estimating daily variation of magnesium concentration. Blood samples are collected at set time points (08:30, 11:00, 12:30, 13:30, 15:00, 16:00 and 18:30). Blood samples are analyzed on the pHOx analyzer for their ionized magnesium concentration. And on the Dimension Vista 1500 from Siemens for their total magnesium concentration.

Interventions

Exercise protocol BEHAVIORAL

70% VO2max bike ergometer test for 90 minutes

Exercise day

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Age: 18 - 45 y
• BMI: 18.5 - 25
• Minimal of 5 hours of training per week, for at least 2 years
• Used to bike, at least 5 hours per week in high season
• No Mg and / or Ca supplementation during study
• No blood donation, during or in the 6 weeks preliminary the study
• Suitable veins
• No chronic medication, with the exception of paracetamol and or birth control
• No antibiotics in the month preliminary the study
• Good health
• Serum Mg \> 0.7 mmol/L
• Willing to give blood
• Able to be present and participate at all test days

You may not qualify if:

• Chronical illness
• Use of medication with the exception of paracetamol and or birth control
• Mg and or Ca supplementation use
• Inadequate Mg intake (according to FFQ)
• Working at Human Nutrition
• Wageningen University Msc thesis or internship at Human Nutrition
• Participating in other scientific research (with the exception of EetMeetWeet)

Sponsors & Collaborators

• Wageningen University: lead
• Gelderse Vallei Hospital: collaborator

MeSH Terms

Conditions

Magnesium Deficiency; Motor Activity

Condition Hierarchy (Ancestors)

Deficiency Diseases; Malnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Behavior

Study Officials

• Jacqueline Klein Gunnewiek, Phd

  Gelderse Vallei Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 9, 2015
• First Posted: February 4, 2016
• Study Start: December 1, 2015
• Primary Completion: March 1, 2016
• Study Completion: March 1, 2016
• Last Updated: February 4, 2016

Record last verified: 2016-02

Data Sharing

• IPD Sharing: Will share