NCT02667314

Brief Summary

Meta-analyses indicate beneficial effects of cognitive training and cognitively challenging video games on cognition. However, cognitive effects of solving jigsaw puzzles - a popular, visuospatial cognitive leisure activity - have not been investigated, yet. Thus, the primary aim of this study is to evaluate the effect of solving jigsaw puzzles on visuospatial cognition. As secondary aims, effects on psychological outcomes (self-efficacy, perceived stress, well-being) and visuospatial everyday functioning (instrumental activities of daily living and self-reported cognitive failures in everyday life) are examined.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2016

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 20, 2016

Completed
8 days until next milestone

First Posted

Study publicly available on registry

January 28, 2016

Completed
4 days until next milestone

Study Start

First participant enrolled

February 1, 2016

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2018

Completed
Last Updated

November 30, 2018

Status Verified

November 1, 2018

Enrollment Period

2 years

First QC Date

January 20, 2016

Last Update Submit

November 28, 2018

Conditions

Keywords

CognitionCognitive AgingDementiaNeurocognitive DisordersCognitive TherapyCognitive ReserveCognitive EnrichmentJigsaw Puzzles

Outcome Measures

Primary Outcomes (1)

  • Change in global visuospatial cognition from baseline to post intervention and to the 1.5-year follow-up

    Averaged score of eight z-standardized visuospatial cognitive ability scores (see secondary outcomes 2 - 9)

    Baseline and post intervention (after 5 weeks and 1.5 years)

Secondary Outcomes (19)

  • Change in visual perception from baseline to post intervention and to the 1.5-year follow-up

    Baseline and post intervention (after 5 weeks and 1.5 years)

  • Change in visuoconstruction from baseline to post intervention and to the 1.5-year follow-up

    Baseline and post intervention (after 5 weeks and 1.5 years)

  • Change in mental rotation from baseline to post intervention and to the 1.5-year follow-up

    Baseline and post intervention (after 5 weeks and 1.5 years)

  • Change in visuospatial processing speed from baseline to post intervention and to the 1.5-year follow-up

    Baseline and post intervention (after 5 weeks and 1.5 years)

  • Change in visuospatial flexibility from baseline to post intervention and to the 1.5-year follow-up

    Baseline and post intervention (after 5 weeks and 1.5 years)

  • +14 more secondary outcomes

Study Arms (2)

Jigsaw Puzzle Group

EXPERIMENTAL

Jigsaw puzzles \& Cognitive health counseling

Behavioral: Jigsaw puzzlesBehavioral: Cognitive health counseling

Cognitive Health Counseling Group

ACTIVE COMPARATOR

Cognitive health counseling only

Behavioral: Cognitive health counseling

Interventions

Jigsaw puzzlesBEHAVIORAL

Intervention period 1: Participants are asked to solve jigsaw puzzles at home 6 times per week for at least 1 hour over a period of 5 weeks. Intervention period 2 (voluntary): Participants receive the possibility to solve jigsaw puzzles free-of-charge at home for a period of at least 3 month before the 1.5-year follow-up.

Jigsaw Puzzle Group

Cognitive health counseling regarding modifiable risk and protective factors of cognitive decline and dementia at baseline, and four telephone calls for expert monitoring (three calls during the 5-week period between pre- and posttest, and one call 12 month later)

Cognitive Health Counseling GroupJigsaw Puzzle Group

Eligibility Criteria

Age50 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • No cognitive impairment (Mini-Mental State Examination ≥ 24)
  • Commitment to minimum jigsaw puzzle time (1 hour/day, 6 days/week, 5 weeks)
  • Interest in jigsaw puzzles
  • Low jigsaw puzzle experience (less than 5 completed puzzles within the last 5 years)

You may not qualify if:

  • Cognitive impairment (Mini-Mental State Examination \< 24)
  • Participation in another interventional study
  • Self-reported psychiatric, neurologic or other disease, which could affect cognitive change over time
  • Self-reported, severe visual impairment or motoric impairment of the upper extremity which significantly affects ability to solve jigsaw puzzles

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Clinical and Biological Psychology, University of Ulm

Ulm, Germany

Location

Related Publications (2)

  • Fissler P, Kuster OC, Loy LS, Laptinskaya D, Rosenfelder MJ, von Arnim CAF, Kolassa IT. Jigsaw Puzzles As Cognitive Enrichment (PACE) - the effect of solving jigsaw puzzles on global visuospatial cognition in adults 50 years of age and older: study protocol for a randomized controlled trial. Trials. 2017 Sep 6;18(1):415. doi: 10.1186/s13063-017-2151-9.

    PMID: 28877756BACKGROUND
  • Fissler P, Kuster OC, Laptinskaya D, Loy LS, von Arnim CAF, Kolassa IT. Jigsaw Puzzling Taps Multiple Cognitive Abilities and Is a Potential Protective Factor for Cognitive Aging. Front Aging Neurosci. 2018 Oct 1;10:299. doi: 10.3389/fnagi.2018.00299. eCollection 2018.

Related Links

MeSH Terms

Conditions

Cognitive DysfunctionDementiaNeurocognitive Disorders

Condition Hierarchy (Ancestors)

Cognition DisordersMental DisordersBrain DiseasesCentral Nervous System DiseasesNervous System Diseases

Study Officials

  • Iris-Tatjana Kolassa, Prof.

    University of Ulm, Germany

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof. Dr.

Study Record Dates

First Submitted

January 20, 2016

First Posted

January 28, 2016

Study Start

February 1, 2016

Primary Completion

February 1, 2018

Study Completion

February 1, 2018

Last Updated

November 30, 2018

Record last verified: 2018-11

Locations