Iatrogenic Effects of Treatment for Childhood Cancer Constitution of a Biological Samples Bank
BIO-F
Study of Iatrogenic Effects of Treatment for Childhood Cancer - Constitution of a Biological Samples Bank as Part of a Cohort of Patients (Cohort FCCSS)
2 other identifiers
observational
6,000
1 country
1
Brief Summary
The constitution of a biological samples bank, attached to epidemiological studies Cohort F-CCSS on iatrogenic effects of treatment of childhood cancer, will identify genetic variants that can modulate the iatrogenic risks of these treatments. The main objective is to provide a biological samples bank to consider, besides the carcinogenic risks, the risk of other iatrogenic diseases in these children, in particular cardiac, cerebrovascular, lung, bone and kidney. These conditions can be very incapacitating and in some cases, fatal. Their impact, however, is poorly estimated as occurring in adulthood, they are rarely made in relation to the treatment received in childhood. The overall project is expected to eventually better define the iatrogenic effects prevention strategies for cancer treatment.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Dec 2010
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2010
CompletedFirst Submitted
Initial submission to the registry
August 3, 2015
CompletedFirst Posted
Study publicly available on registry
January 28, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2017
CompletedJune 9, 2016
June 1, 2016
7 years
August 3, 2015
June 8, 2016
Conditions
Outcome Measures
Primary Outcomes (1)
Study of genetic factors who might lead to secondary iatrogenic pathology due to treatment of a childhood cancer
seven years
Study Arms (1)
Patients treated for cancer in childhood
Interventions
Eligibility Criteria
Patients treated for a paediatric malignancies before the year 2000 having survived two years after treatment of solid tumor diagnosed before 18 years old
You may qualify if:
- Patients treated for a first cancer in childhood
- Adult patients
- Signed informed consent
- Patient insured or enjoying a social security scheme
You may not qualify if:
- Minor patients
- Under legal protection measure patients
- Refusal of consent
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Gustave Roussy Cancer Campus Grand Paris
Villejuif, Val de Marne, 94805, France
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 7 Years
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
August 3, 2015
First Posted
January 28, 2016
Study Start
December 1, 2010
Primary Completion
December 1, 2017
Study Completion
December 1, 2017
Last Updated
June 9, 2016
Record last verified: 2016-06