Assessing the Effect of Periodontal Debridement, Tongue Cleaning and Mouth Rinsing for the Treatment of Oral Malodour

NCT02665780 | Withdrawn

• 1 other identifier: H15-02159
• Study Type: interventional
• Target: N/A
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study evaluates the short and long term effect of dental cleaning and mouthrinsing for the treatment of bad breath

Conditions

Halitosis

Keywords

halitosis, periodontal debridement, chemotherapeutics

Outcome Measures

Primary Outcomes (1)

• Reduction of oral malodour below threshold

  1, 12, 24 weeks

Study Arms (1)

Treatment

EXPERIMENTAL

Periodontal debridement, tongue cleaning, mouth rinsing with 20ml Cetylpyridium Chloride daily for 24 weeks

Procedure: Periodontal debridement; Other: Cetylpyridium chloride

Interventions

Periodontal debridement PROCEDURE

teeth cleaning

Treatment

Cetylpyridium chloride OTHER

mouthrinse

Treatment

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Organoleptic score of 2 or more, and volatile sulfur compound score of greater than 1.5ng/10ml of hydrogen sulfide and 0.5ng/10ml of methyl mercaptan

You may not qualify if:

• Moderate to severe periodontal disease, systemic illness or dental disease associated with halitosis, antibiotic use in the past month, need for antibiotic prophylaxis for dental procedures and current smokers

Sponsors & Collaborators

• University of British Columbia: lead

MeSH Terms

Conditions

Halitosis

Interventions

Periodontal Debridement; Cetylpyridinium

Condition Hierarchy (Ancestors)

Signs and Symptoms, Digestive; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Dental Prophylaxis; Periodontics; Dentistry; Pyridinium Compounds; Pyridines; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds

Study Officials

• Leeann Donnelly, PhD

  University of British Columbia

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor, Dept. Oral Biological and Medical Sciences

Study Record Dates

• First Submitted: January 25, 2016
• First Posted: January 28, 2016
• Study Start: October 1, 2017
• Primary Completion: October 10, 2018
• Study Completion: October 10, 2018
• Last Updated: October 15, 2018

Record last verified: 2018-10

Data Sharing

• IPD Sharing: Will not share