Mortality in Cancer Patients Admitted to the Intensive Care Unit in a Resource-limited Setting

NCT02659839 | Completed

• 1 other identifier: 101015
• Study Type: observational
• Target: 142
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to determine 30 day mortality in cancer patients admitted to the intensive care unit in a resource limited setting.

Conditions

Cancer

Keywords

Cancer; Intensive care unit; Mortality

Outcome Measures

Primary Outcomes (1)

• Mortality at 30 days

  30 days since ICU admission

Secondary Outcomes (1)

• Mortality at 180 days

  180 days since ICU admission

Study Arms (1)

Cancer patients admitted to the ICU

Patients with cancer admitted to the ICU. No intervention will be administered.

Other: Cancer patients admitted to the ICU

Interventions

Cancer patients admitted to the ICU OTHER

There will be no change in the standard ICU treatment.

Also known as: Standard intensive care unit management.

Cancer patients admitted to the ICU

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patient with histological diagnosis or high clinical suspicious of cancer, admitted to the intensive care unit

You may qualify if:

• years-old or older
• Histological diagnosis or high clinical suspicious of cancer (solid /hematological), with the exception of non-melanoma skin cancer.
• Functional classification state between 0-3, according to Eastern Cooperative Oncology Group.
• Admission to intensive care unit, because of one or more of the following criteria:
• Invasive or non-invasive ventilatory support due to acute respiratory failure.
• Use of vasopressor drugs due to hypotension defined as noradrenaline requirement higher than 0.1 microgram/Kg/min.
• Renal replacement therapy due to acute renal failure.

You may not qualify if:

• Absence of cancer recurrences in more than 5 years after diagnosis
• Functional classification state of 4, according to Eastern Cooperative Oncology Group.

Sponsors & Collaborators

• Pontificia Universidad Catolica de Chile: lead

Study Sites (1)

Hospital Dr. Sótero del Rio

Santiago, Santiago Metropolitan, 8207257, Chile

Location

Related Publications (1)

• Panay S, Ruiz C, Abarca M, Nervi B, Salazar I, Caro P, Muniz S, Briones J, Bruhn A, Mondaca S. Mortality of Adult Patients With Cancer Admitted to an Intensive Care Unit in Chile: A Prospective Cohort Study. J Glob Oncol. 2018 Dec;4:1-9. doi: 10.1200/JGO.18.00091.

  PMID: 30582431 DERIVED

MeSH Terms

Conditions

Neoplasms

Study Officials

• Sebastián Mondaca, MD

  Pontificia Universidad Catolica de Chile

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 16, 2016
• First Posted: January 20, 2016
• Study Start: July 1, 2015
• Primary Completion: October 1, 2016
• Study Completion: October 1, 2016
• Last Updated: October 27, 2016

Record last verified: 2016-10

Locations

CL (1)