NCT02658903

Brief Summary

The safety and efficacy of a urinary catheter designed to prevent catheter associated urinary infections is studied.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
54

participants targeted

Target at P50-P75 for phase_1

Timeline
Completed

Started Jan 2016

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 20, 2015

Completed
1 month until next milestone

Study Start

First participant enrolled

January 1, 2016

Completed
19 days until next milestone

First Posted

Study publicly available on registry

January 20, 2016

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2017

Completed
Last Updated

January 20, 2016

Status Verified

January 1, 2016

Enrollment Period

1 year

First QC Date

November 20, 2015

Last Update Submit

January 19, 2016

Conditions

Keywords

FoleyInfectionHospital acquiredcatheter associatedurinary

Outcome Measures

Primary Outcomes (1)

  • Bacterial biofilm on catheter, assessed by ultrasonic culture of catheter tip removed at the end of the study.

    4 weeks

Secondary Outcomes (3)

  • Significant bacteriuria assessed by weekly bacterial cultures.

    every week during 4 weeks

  • Clinically symptomatic catheter associated lower urinary infections.

    4 weeks

  • occurence of adverse events

    within 4 weeks

Study Arms (2)

Study arm with Oxys-Cathter

EXPERIMENTAL

The study group is treated with a modified urinary catheter, which delivers electromagnetic therapy to prevent and treat bacterial colonization during the study period. The intervention is the insertion of the study urinary catheter (foley) into the bladder.

Device: Oxys Catheter

Control-arm with commercial catheter

OTHER

The control group is treated with a commercial urinary catheter. The intervention is the insertion of the control urinary catheter (foley) into the bladder,

Device: Covidien Mona-Therm Foley catheter

Interventions

The study catheter is inserted over the urethra in the bladder as a foley catheter. The study foley catheter delivers electromagnetic therapy.

Study arm with Oxys-Cathter

The control arm catheter is inserted over the urethra in the bladder. The control catheter is a Mona-Therm catheter from Covidien.

Control-arm with commercial catheter

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient with need for an indwelling urinary catheter to be placed at least for 4 weeks, which are willing and capable to provide informed consent. Most patients have spinal cord injury and are treated by the prinicpal investigator.

You may not qualify if:

  • Need for antibiotic treatment for any infections
  • Urological intervention or need for catheter change within study duration of 4 weeks

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital Balgrist

Zurich, Canton of Zurich, 8008, Switzerland

RECRUITING

MeSH Terms

Conditions

Infections

Study Officials

  • Thomas Kessler, MD

    Universitätsklinik Balgrist Zürich

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Christoph Scharf, MD

CONTACT

Christine Tivig, MD

CONTACT

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 20, 2015

First Posted

January 20, 2016

Study Start

January 1, 2016

Primary Completion

January 1, 2017

Study Completion

January 1, 2017

Last Updated

January 20, 2016

Record last verified: 2016-01

Locations