NCT02658643

Brief Summary

The aim of this prospective randomized controlled study is to determine the benefit-risk ratio (success rate, complication rate, tolerance) for patients with biliodigestive anastomosis by either continuous or interrupted suture.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2016

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 15, 2016

Completed
5 days until next milestone

First Posted

Study publicly available on registry

January 20, 2016

Completed
Same day until next milestone

Study Start

First participant enrolled

January 20, 2016

Completed
3.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 17, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 17, 2019

Completed
Last Updated

October 22, 2019

Status Verified

October 1, 2019

Enrollment Period

3.7 years

First QC Date

January 15, 2016

Last Update Submit

October 21, 2019

Conditions

Keywords

biliodigestive anastomosis techniques

Outcome Measures

Primary Outcomes (1)

  • Time to complete the biliodigestive anastomosis

    30 minutes

Study Arms (2)

Continuous suture technique

EXPERIMENTAL

The BDA is performed as continuous suture with two separate all-layer suture for the behind - and front-wall of the anastomosis

Procedure: Continuous suture technique

Interrupted suture technique

ACTIVE COMPARATOR

The BDA is performed as interrupted suture with two separate all-layer suture for the behind - and front-wall of the anastomosis

Procedure: Interrupted suture technique

Interventions

The BDA is performed as continuous suture with two separate all-layer suture for the behind - and front-wall of the anastomosis

Continuous suture technique

The BDA is performed as interrupted suture with two separate all-layer suture for the behind - and front-wall of the anastomosis

Interrupted suture technique

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients over 18 years of age
  • Scheduled for elective BDA procedure
  • Primary BDA procedure
  • Diameter of DHC \> 7mm
  • Written consent

You may not qualify if:

  • Previous BDA procedure
  • Impaired mental state or language problems
  • Lacking compliance
  • Emergency procedure

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, TU Dresden, Germany

Dresden, Germany

Location

Related Publications (1)

  • Seifert L, von Renesse J, Seifert AM, Sturm D, Meisterfeld R, Rahbari NN, Kahlert C, Distler M, Weitz J, Reissfelder C. Interrupted versus continuous suture technique for biliary-enteric anastomosis: randomized clinical trial. BJS Open. 2023 Jan 6;7(1):zrac163. doi: 10.1093/bjsopen/zrac163.

Study Officials

  • Christoph Reißfelder, MD

    christoph.reissfelder@uniklinikum-dresden.de

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 15, 2016

First Posted

January 20, 2016

Study Start

January 20, 2016

Primary Completion

September 17, 2019

Study Completion

September 17, 2019

Last Updated

October 22, 2019

Record last verified: 2019-10

Locations